SYNTHESIS OF NEW SERIES OF THIENYL ACRYLATE DERIVATIVES VIA BAYLIS-HILLMAN REACTION AND EVALUATION OF ANTIMICROBIAL ACTIVITY

SYNTHESIS OF NEW SERIES OF THIENYL ACRYLATE DERIVATIVES VIA BAYLIS-HILLMAN REACTION AND EVALUATION OF ANTIMICROBIAL ACTIVITY

A series of new Thienyl acrylate compounds were synthesized via Baylis-Hillman reaction and tested to demonstrate in vitro antimicrobial activity. Some of these compounds exhibited a very good activity against Gram positive strains. The structure of these newly synthesized compounds were conformed b...

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Veröffentlicht in:International journal of pharmaceutical sciences and research 2011-04, Vol.2 (4), p.893-893
Hauptverfasser: Sivadas, Anand, Satyaseela, Maneesh Paul, Bharani, Thirunavukkarasu, Upparapalli, Sampath Kumar, Subbaraya, Narayanan
Format: Artikel
Sprache:eng
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Zusammenfassung:A series of new Thienyl acrylate compounds were synthesized via Baylis-Hillman reaction and tested to demonstrate in vitro antimicrobial activity. Some of these compounds exhibited a very good activity against Gram positive strains. The structure of these newly synthesized compounds were conformed by super( 1)H NMR, IR, Mass and Elemental analysis, some of them were also confirmed by super( 13)C NMR.
ISSN:0975-8232
DOI:10.13040/IJPSR.0975-8232.2(4).893.04