Poloxamer 188 attenuates in vitro traumatic brain injury-induced mitochondrial and lysosomal membrane permeabilization damage in cultured primary neurons

Acute membrane damage due to traumatic brain injury (TBI) is a critical precipitating event. However, the subsequent effects of the mechanical trauma, including mitochondrial and lysosomal membrane permeability (MOMP and LMP) remain elusive. The main objective of the current study was to assess the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurotrauma 2013-04, Vol.30 (7), p.597-607
Hauptverfasser:	Luo, Cheng-Liang, Chen, Xi-Ping, Li, Li-Liang, Li, Qian-Qian, Li, Bei-Xu, Xue, Ai-Min, Xu, Hong-Fei, Dai, Ding-Kun, Shen, Yi-Wen, Tao, Lu-Yang, Zhao, Zi-Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Brain damage Brain Injuries - metabolism Brain Injuries - pathology Cells, Cultured Cellular biology Head injuries Intracellular Membranes - drug effects Intracellular Membranes - metabolism Intracellular Membranes - pathology Lysosomes - drug effects Lysosomes - metabolism Lysosomes - pathology Membrane Potential, Mitochondrial - drug effects Mitochondria - drug effects Mitochondria - metabolism Mitochondria - pathology Neurons Neurons - drug effects Neurons - metabolism Neurons - pathology Neuroprotective Agents - pharmacology Permeability Poloxamer - pharmacology Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!