Hydroxyurea treatment can avoid the need for aggressive surgery in pediatric fibromatosis

Hydroxyurea treatment can avoid the need for aggressive surgery in pediatric fibromatosis

Aggressive fibromatosis is a rare tumor of borderline malignancy with a marked local aggressiveness. Surgery is the mainstay of treatment but complete tumor resection is often not easy to achieve without functional and cosmetic sequelae. We report a case of a pretreated child with aggressive fibroma...

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Veröffentlicht in:Journal of pediatric hematology/oncology 2013-05, Vol.35 (4), p.e171-e173
Hauptverfasser: Bisogno, Gianni, Tagarelli, Arianna, Stramare, Roberto, Beltrame, Valeria, Carli, Modesto
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Antineoplastic Agents - therapeutic use
Fibromatosis, Aggressive - drug therapy
Fibromatosis, Aggressive - surgery
Humans
Hydroxyurea - therapeutic use
Male
Soft Tissue Neoplasms - drug therapy
Soft Tissue Neoplasms - surgery
Thigh - pathology
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container_issue 4
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container_title Journal of pediatric hematology/oncology
container_volume 35
creator Bisogno, Gianni
Tagarelli, Arianna
Stramare, Roberto
Beltrame, Valeria
Carli, Modesto
description Aggressive fibromatosis is a rare tumor of borderline malignancy with a marked local aggressiveness. Surgery is the mainstay of treatment but complete tumor resection is often not easy to achieve without functional and cosmetic sequelae. We report a case of a pretreated child with aggressive fibromatosis who responded to hydroxyurea, avoiding the need for demolitive surgery.
doi_str_mv 10.1097/MPH.0b013e3182678d25
format Article
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subjects Adolescent
Antineoplastic Agents - therapeutic use
Fibromatosis, Aggressive - drug therapy
Fibromatosis, Aggressive - surgery
Humans
Hydroxyurea - therapeutic use
Male
Soft Tissue Neoplasms - drug therapy
Soft Tissue Neoplasms - surgery
Thigh - pathology
title Hydroxyurea treatment can avoid the need for aggressive surgery in pediatric fibromatosis
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