Second line treatment of metastatic renal cell carcinoma: The Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients

Abstract Background Sequential treatment is currently the standard of care in metastatic renal cell carcinoma (mRCC). However, very little is known on how many patients (pts) can receive second line or further, and on how to predict those pts. The goal of this study was to evaluate these questions i...

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Veröffentlicht in:	European journal of cancer (1990) 2013-05, Vol.49 (8), p.1898-1904
Hauptverfasser:	Levy, Antonin, Menard, Jean, Albiges, Laurence, Loriot, Yohann, Di Palma, Mario, Fizazi, Karim, Escudier, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Analysis of Variance Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - adverse effects Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bevacizumab Biological and medical sciences Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - pathology Cardiovascular Diseases - chemically induced Disease Progression Drug Administration Schedule Everolimus Female Follow-Up Studies Hematology, Oncology and Palliative Medicine Humans Indoles - administration & dosage Indoles - adverse effects Kaplan-Meier Estimate Kidney Neoplasms - drug therapy Kidney Neoplasms - pathology Male Medical sciences Metastatic renal cell carcinoma Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Metastasis Niacinamide - administration & dosage Niacinamide - adverse effects Niacinamide - analogs & derivatives Pharmacology. Drug treatments Phenylurea Compounds - administration & dosage Phenylurea Compounds - adverse effects Pyrroles - administration & dosage Pyrroles - adverse effects Second line Sirolimus - administration & dosage Sirolimus - adverse effects Sirolimus - analogs & derivatives Targeted therapy Treatment Outcome Tumors Young Adult
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