Sentinel lymph node biopsy for melanoma: A critical update for dermatologists after two decades of experience
Abstract The technique of lymphatic mapping and sentinel node biopsy represents a minimally invasive approach to accurately stage the regional lymph node basin as a component of the initial management of selected patients with stage I and II cutaneous melanomas. In addition to its significant role i...
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Veröffentlicht in: | Clinics in dermatology 2013-05, Vol.31 (3), p.298-310 |
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creator | Ross, Merrick I., MD Gershenwald, Jeffrey E., MD |
description | Abstract The technique of lymphatic mapping and sentinel node biopsy represents a minimally invasive approach to accurately stage the regional lymph node basin as a component of the initial management of selected patients with stage I and II cutaneous melanomas. In addition to its significant role in accurate regional nodal staging and prognosis, important goals of this procedure include improved regional disease control and possible survival benefit. After 20 years of experience, questions and some controversy persist. This review provides the dermatology community with a critical analysis of major publications that have defined the role of sentinel node biopsy, addresses several contemporary issues, and provides recommendations for appropriate patient referral. |
doi_str_mv | 10.1016/j.clindermatol.2012.08.004 |
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In addition to its significant role in accurate regional nodal staging and prognosis, important goals of this procedure include improved regional disease control and possible survival benefit. After 20 years of experience, questions and some controversy persist. This review provides the dermatology community with a critical analysis of major publications that have defined the role of sentinel node biopsy, addresses several contemporary issues, and provides recommendations for appropriate patient referral.</description><identifier>ISSN: 0738-081X</identifier><identifier>EISSN: 1879-1131</identifier><identifier>DOI: 10.1016/j.clindermatol.2012.08.004</identifier><identifier>PMID: 23608449</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Dermatology ; Humans ; Lymph Nodes - pathology ; Lymphatic Metastasis ; Melanoma - secondary ; Neoplasm Staging ; Patient Selection ; Prognosis ; Risk Factors ; Sentinel Lymph Node Biopsy - methods ; Skin Neoplasms - pathology ; Time Factors</subject><ispartof>Clinics in dermatology, 2013-05, Vol.31 (3), p.298-310</ispartof><rights>2013</rights><rights>Copyright © 2013. 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This review provides the dermatology community with a critical analysis of major publications that have defined the role of sentinel node biopsy, addresses several contemporary issues, and provides recommendations for appropriate patient referral.</description><subject>Dermatology</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Melanoma - secondary</subject><subject>Neoplasm Staging</subject><subject>Patient Selection</subject><subject>Prognosis</subject><subject>Risk Factors</subject><subject>Sentinel Lymph Node Biopsy - methods</subject><subject>Skin Neoplasms - pathology</subject><subject>Time Factors</subject><issn>0738-081X</issn><issn>1879-1131</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1v1DAQQC0EokvhLyCLE5eEceIkTg9IVaGAVKmHFomb5bXH4CWJg-0A--_rdNuq4sTB8mHefL0h5A2DkgFr3-1KPbjJYBhV8kNZAatKECUAf0I2THR9wVjNnpINdLUoQLBvR-RFjDvIBLTwnBxVdQuC835DxiuckptwoMN-nH_QyRukW-fnuKfWBzrioCY_qhN6SnVwyWk10GU2KuFt_H4K_93FFKmyCQNNf3wOaGUwUm8p_p0xOJw0viTPrBoivrr7j8nX84_XZ5-Li8tPX85OLwrN6yYVBhvWGVRgsW_zE41SWlWixw7qfttia6sc65TNIBjNUfU95xYFNMoyUR-Tt4e6c_C_FoxJji5qHPIu6JcoWc2bhlVQ84yeHFAdfIwBrZyDG1XYSwZy1S138rFuueqWIGSWmZNf3_VZtiOah9R7vxn4cAAwb_vbYZBR35owLqBO0nj3f33e_1NmRddb_MQ9xp1fwpR9SiZjzpFX6-HXu-cVgXW8qW8AnAivvQ</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>Ross, Merrick I., MD</creator><creator>Gershenwald, Jeffrey E., MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130501</creationdate><title>Sentinel lymph node biopsy for melanoma: A critical update for dermatologists after two decades of experience</title><author>Ross, Merrick I., MD ; Gershenwald, Jeffrey E., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-de517dea0fe96fe985aaca289e7039b6e6f20fe7afe510dc4ea9944fe805af183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Dermatology</topic><topic>Humans</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis</topic><topic>Melanoma - secondary</topic><topic>Neoplasm Staging</topic><topic>Patient Selection</topic><topic>Prognosis</topic><topic>Risk Factors</topic><topic>Sentinel Lymph Node Biopsy - methods</topic><topic>Skin Neoplasms - pathology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ross, Merrick I., MD</creatorcontrib><creatorcontrib>Gershenwald, Jeffrey E., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinics in dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ross, Merrick I., MD</au><au>Gershenwald, Jeffrey E., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sentinel lymph node biopsy for melanoma: A critical update for dermatologists after two decades of experience</atitle><jtitle>Clinics in dermatology</jtitle><addtitle>Clin Dermatol</addtitle><date>2013-05-01</date><risdate>2013</risdate><volume>31</volume><issue>3</issue><spage>298</spage><epage>310</epage><pages>298-310</pages><issn>0738-081X</issn><eissn>1879-1131</eissn><abstract>Abstract The technique of lymphatic mapping and sentinel node biopsy represents a minimally invasive approach to accurately stage the regional lymph node basin as a component of the initial management of selected patients with stage I and II cutaneous melanomas. In addition to its significant role in accurate regional nodal staging and prognosis, important goals of this procedure include improved regional disease control and possible survival benefit. After 20 years of experience, questions and some controversy persist. This review provides the dermatology community with a critical analysis of major publications that have defined the role of sentinel node biopsy, addresses several contemporary issues, and provides recommendations for appropriate patient referral.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>23608449</pmid><doi>10.1016/j.clindermatol.2012.08.004</doi><tpages>13</tpages></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Dermatology Humans Lymph Nodes - pathology Lymphatic Metastasis Melanoma - secondary Neoplasm Staging Patient Selection Prognosis Risk Factors Sentinel Lymph Node Biopsy - methods Skin Neoplasms - pathology Time Factors |
title | Sentinel lymph node biopsy for melanoma: A critical update for dermatologists after two decades of experience |
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