Revealing the Mechanism of Tissue Damage Due to Tobacco Use: Finally, a Smoking Gun?

Revealing the Mechanism of Tissue Damage Due to Tobacco Use: Finally, a Smoking Gun?

This Commentary highlights the article by Li et al that presents a compelling case for a mechanism by which tobacco smoke extract (TSE) induces damage to the extracellular matrix, a key element in the pathogenesis of tobacco-related disease.

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Bibliographische Detailangaben
Veröffentlicht in:The American journal of pathology 2013-05, Vol.182 (5), p.1489-1493
1. Verfasser: Furmanski, Philip
Format: Artikel
Sprache:eng
Schlagworte:
Cell-Derived Microparticles - metabolism
Humans
Macrophages - metabolism
Proteolysis
Smoking
Online-Zugang:Volltext
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Zusammenfassung:This Commentary highlights the article by Li et al that presents a compelling case for a mechanism by which tobacco smoke extract (TSE) induces damage to the extracellular matrix, a key element in the pathogenesis of tobacco-related disease.
ISSN:0002-9440
1525-2191
DOI:10.1016/j.ajpath.2013.02.004