Blood oxygenation level-dependent (BOLD) contrast magnetic resonance imaging (MRI) for prediction of breast cancer chemotherapy response: A pilot study

Purpose: To determine whether a simple noninvasive method of assessing tumor oxygenation is feasible in the clinical setting and can provide useful, potentially predictive information. Tumor microcirculation and oxygenation play critical roles in tumor growth and responsiveness to cytotoxic treatmen...

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Veröffentlicht in:	Journal of magnetic resonance imaging 2013-05, Vol.37 (5), p.1083-1092
Hauptverfasser:	Jiang, Lan, Weatherall, Paul T., McColl, Roderick W., Tripathy, Debu, Mason, Ralph P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Combined Chemotherapy Protocols - administration & dosage Biomarkers, Tumor - blood BOLD MRI breast cancer Breast Neoplasms - blood Breast Neoplasms - diagnosis Breast Neoplasms - drug therapy Contrast Media - analysis Cyclophosphamide - administration & dosage Doxorubicin - administration & dosage Female Humans Image Interpretation, Computer-Assisted - methods Magnetic resonance imaging Magnetic Resonance Imaging - methods Middle Aged neoadjuvant chemotherapy oxygen Oxygen - blood Paclitaxel - administration & dosage prognosis Reproducibility of Results Sensitivity and Specificity Treatment Outcome
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