Temperature threshold testing: a systematic review

The diagnosis of small fiber neuropathy (SFN) has been recently defined as typical symptoms due to small nerve fiber dysfunction accompanied by reduced intra‐epidermal nerve fiber density (IENFD) or abnormal temperature threshold testing (TTT). Guidelines have been published for the assessment of IE...

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Veröffentlicht in:Journal of the peripheral nervous system 2013-03, Vol.18 (1), p.7-18
Hauptverfasser: Bakkers, Mayienne, Faber, Catharina G., Peters, Martine J. H., Reulen, Jos P. H., Franssen, Hessel, Fischer, Tanya Z., Merkies, Ingemar S. J.
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container_issue 1
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container_title Journal of the peripheral nervous system
container_volume 18
creator Bakkers, Mayienne
Faber, Catharina G.
Peters, Martine J. H.
Reulen, Jos P. H.
Franssen, Hessel
Fischer, Tanya Z.
Merkies, Ingemar S. J.
description The diagnosis of small fiber neuropathy (SFN) has been recently defined as typical symptoms due to small nerve fiber dysfunction accompanied by reduced intra‐epidermal nerve fiber density (IENFD) or abnormal temperature threshold testing (TTT). Guidelines have been published for the assessment of IENFD. However, international guidelines for TTT are lacking. This paper presents a systematic literature review on reported TTT methods and provides recommendations for its future use in studies evaluating patients. A total of 164 papers fulfilled pre‐defined requirements and were selected for review. Over 15 types of instruments are currently being used with a variety of methodological approaches for location, stimulus application, and sensation qualities examined. Consensus is needed to standardize the use of TTT as a diagnostic and follow‐up tool in patients.
doi_str_mv 10.1111/jns5.12001
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source Wiley Online Library - AutoHoldings Journals; MEDLINE
subjects Animals
Humans
Peripheral Nervous System Diseases - diagnosis
Peripheral Nervous System Diseases - physiopathology
quantitative sensory testing
Sensory Thresholds - physiology
small fiber neuropathy
Studies
Temperature
temperature threshold testing
Thermosensing - physiology
title Temperature threshold testing: a systematic review
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