Repeatability of the Six-Minute Walk Test and Relation to Physical Function in Survivors of a Critical Illness

The Six-Minute Walk Test (6MWT) is widely used as an outcome measure in exercise rehabilitation. However, the repeatability of the 6MWT performed at home in survivors of a critical illness has not been evaluated. The purpose of this study was to evaluate, in survivors of a critical illness: (1) the...

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Veröffentlicht in:Physical therapy 2012-12, Vol.92 (12), p.1556-1563
Hauptverfasser: Alison, Jennifer A, Kenny, Patricia, King, Madeleine T, McKinley, Sharon, Aitken, Leanne M, Leslie, Gavin D, Elliott, Doug
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container_end_page 1563
container_issue 12
container_start_page 1556
container_title Physical therapy
container_volume 92
creator Alison, Jennifer A
Kenny, Patricia
King, Madeleine T
McKinley, Sharon
Aitken, Leanne M
Leslie, Gavin D
Elliott, Doug
description The Six-Minute Walk Test (6MWT) is widely used as an outcome measure in exercise rehabilitation. However, the repeatability of the 6MWT performed at home in survivors of a critical illness has not been evaluated. The purpose of this study was to evaluate, in survivors of a critical illness: (1) the repeatability of the 6MWT performed at home, (2) the effect on estimates of change in functional exercise capacity if only one 6MWT was performed at follow-up assessments, and (3) the relationship between the physical functioning (PF) score of the 36-Item Short-Form Health Survey questionnaire (SF-36) and the 6MWT. Repeated measures of the 6MWT and SF-36 were obtained. Eligible participants had an intensive care unit (ICU) length of stay of ≥48 hours and were mechanically ventilated for ≥24 hours. Two 6MWTs and the SF-36 were conducted in participants' homes at weeks 1, 8, and 26 after hospital discharge. One hundred seventy-three participants completed the study. The participants had a mean age of 57 years (SD=16), a mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score on admission of 19 (SD=10), a mean ICU length of stay of 9 days (SD=8), and a mean mechanical ventilation time of 140 hours (SD=137). Of the 173 participants, 110 performed two 6MWTs at weeks 1, 8, and 26. There were significant mean increases in 6-minute walk distance in the second test of 15 m (P
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However, the repeatability of the 6MWT performed at home in survivors of a critical illness has not been evaluated. The purpose of this study was to evaluate, in survivors of a critical illness: (1) the repeatability of the 6MWT performed at home, (2) the effect on estimates of change in functional exercise capacity if only one 6MWT was performed at follow-up assessments, and (3) the relationship between the physical functioning (PF) score of the 36-Item Short-Form Health Survey questionnaire (SF-36) and the 6MWT. Repeated measures of the 6MWT and SF-36 were obtained. Eligible participants had an intensive care unit (ICU) length of stay of ≥48 hours and were mechanically ventilated for ≥24 hours. Two 6MWTs and the SF-36 were conducted in participants' homes at weeks 1, 8, and 26 after hospital discharge. One hundred seventy-three participants completed the study. The participants had a mean age of 57 years (SD=16), a mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score on admission of 19 (SD=10), a mean ICU length of stay of 9 days (SD=8), and a mean mechanical ventilation time of 140 hours (SD=137). Of the 173 participants, 110 performed two 6MWTs at weeks 1, 8, and 26. There were significant mean increases in 6-minute walk distance in the second test of 15 m (P<.0001) at week 1, 13 m (P<.0001) at week 8, and 9 m (P=.04) at week 26. If only one 6MWT was performed at weeks 8 and 26, the estimate of change in 6-minute walk distance from week 1 was 19 m less (P<.001) at both weeks 8 and 26. There was a moderate to strong correlation between SF-36 PF score and 6-minute walk distance at each assessment (week 1: r=.62, P<.001; week 8: r=.55, P<.001; and week 26: r=.47, P<.001). Some study participants were unable to perform a second 6MWT, and these participants may have differed in important aspects of function compared with those individuals who completed two 6MWTs. In survivors of a critical illness, the 6MWT in the home environment should be performed twice at each assessment to give an accurate reflection of change in exercise capacity over time. The SF-36 PF score was a strong indicator of 6-minute walk distance in early recovery from a critical illness.]]></description><identifier>ISSN: 0031-9023</identifier><identifier>EISSN: 1538-6724</identifier><identifier>DOI: 10.2522/ptj.20110410</identifier><identifier>PMID: 22577064</identifier><language>eng</language><publisher>United States: American Physical Therapy Association</publisher><subject>Care and treatment ; Confidence intervals ; Critical Illness - rehabilitation ; Critically ill ; Critically ill persons ; Disability Evaluation ; Exercise Test ; Exercise tests ; Exercise Tolerance ; Female ; Follow-Up Studies ; Health aspects ; Home Care Services ; Humans ; Illnesses ; Intensive Care Units ; Male ; Methods ; Middle Aged ; Older people ; Outcome and process assessment (Health Care) ; Outcome and process assessment (Medical care) ; Outcome Assessment (Health Care) - methods ; Rehabilitation ; Reproducibility of Results ; Respiration, Artificial ; Studies ; Survivors</subject><ispartof>Physical therapy, 2012-12, Vol.92 (12), p.1556-1563</ispartof><rights>COPYRIGHT 2012 Oxford University Press</rights><rights>COPYRIGHT 2012 Oxford University Press</rights><rights>Copyright AMERICAN PHYSICAL THERAPY ASSOCIATION Dec 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c772t-656eefcdd238b5160259806498c2de8043ca380de8abe1feb7c30b7b10b2ba0d3</citedby><cites>FETCH-LOGICAL-c772t-656eefcdd238b5160259806498c2de8043ca380de8abe1feb7c30b7b10b2ba0d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22577064$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alison, Jennifer A</creatorcontrib><creatorcontrib>Kenny, Patricia</creatorcontrib><creatorcontrib>King, Madeleine T</creatorcontrib><creatorcontrib>McKinley, Sharon</creatorcontrib><creatorcontrib>Aitken, Leanne M</creatorcontrib><creatorcontrib>Leslie, Gavin D</creatorcontrib><creatorcontrib>Elliott, Doug</creatorcontrib><title>Repeatability of the Six-Minute Walk Test and Relation to Physical Function in Survivors of a Critical Illness</title><title>Physical therapy</title><addtitle>Phys Ther</addtitle><description><![CDATA[The Six-Minute Walk Test (6MWT) is widely used as an outcome measure in exercise rehabilitation. However, the repeatability of the 6MWT performed at home in survivors of a critical illness has not been evaluated. The purpose of this study was to evaluate, in survivors of a critical illness: (1) the repeatability of the 6MWT performed at home, (2) the effect on estimates of change in functional exercise capacity if only one 6MWT was performed at follow-up assessments, and (3) the relationship between the physical functioning (PF) score of the 36-Item Short-Form Health Survey questionnaire (SF-36) and the 6MWT. Repeated measures of the 6MWT and SF-36 were obtained. Eligible participants had an intensive care unit (ICU) length of stay of ≥48 hours and were mechanically ventilated for ≥24 hours. Two 6MWTs and the SF-36 were conducted in participants' homes at weeks 1, 8, and 26 after hospital discharge. One hundred seventy-three participants completed the study. The participants had a mean age of 57 years (SD=16), a mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score on admission of 19 (SD=10), a mean ICU length of stay of 9 days (SD=8), and a mean mechanical ventilation time of 140 hours (SD=137). Of the 173 participants, 110 performed two 6MWTs at weeks 1, 8, and 26. There were significant mean increases in 6-minute walk distance in the second test of 15 m (P<.0001) at week 1, 13 m (P<.0001) at week 8, and 9 m (P=.04) at week 26. If only one 6MWT was performed at weeks 8 and 26, the estimate of change in 6-minute walk distance from week 1 was 19 m less (P<.001) at both weeks 8 and 26. There was a moderate to strong correlation between SF-36 PF score and 6-minute walk distance at each assessment (week 1: r=.62, P<.001; week 8: r=.55, P<.001; and week 26: r=.47, P<.001). Some study participants were unable to perform a second 6MWT, and these participants may have differed in important aspects of function compared with those individuals who completed two 6MWTs. In survivors of a critical illness, the 6MWT in the home environment should be performed twice at each assessment to give an accurate reflection of change in exercise capacity over time. The SF-36 PF score was a strong indicator of 6-minute walk distance in early recovery from a critical illness.]]></description><subject>Care and treatment</subject><subject>Confidence intervals</subject><subject>Critical Illness - rehabilitation</subject><subject>Critically ill</subject><subject>Critically ill persons</subject><subject>Disability Evaluation</subject><subject>Exercise Test</subject><subject>Exercise tests</subject><subject>Exercise Tolerance</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health aspects</subject><subject>Home Care Services</subject><subject>Humans</subject><subject>Illnesses</subject><subject>Intensive Care Units</subject><subject>Male</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Older people</subject><subject>Outcome and process assessment (Health Care)</subject><subject>Outcome and process assessment (Medical care)</subject><subject>Outcome Assessment (Health Care) - methods</subject><subject>Rehabilitation</subject><subject>Reproducibility of Results</subject><subject>Respiration, Artificial</subject><subject>Studies</subject><subject>Survivors</subject><issn>0031-9023</issn><issn>1538-6724</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqV089v0zAUB_AIgdgY3DgjS1xAIsV26tg5ThUblQpD3RBHy3FeWg_XKbYz1v8e98eAogqGcnBkffxs6-uXZc8JHlBG6dtlvB5QTAgeEvwgOyasEHnJ6fBhdoxxQfIK0-IoexLCNcaY8GH1ODuilHGOy-Fx5qawBBVVbayJK9S1KM4BXZrb_INxfQT0Rdmv6ApCRMo1aApWRdM5FDv0ab4KRiuLznqnN5PGocve35ibzod1KYVG3sSNGVvrIISn2aNW2QDPduNJ9vns3dXofT65OB-PTie55pzGvGQlQKubhhaiZqTElFUinbcSmjYg8LDQqhA4_aoaSAs11wWueU1wTWuFm-Ike7Wtu_Tdtz6dXi5M0GCtctD1QZKClUKwipJ7UCoY4aWg_6aUEsEwpzzRl3_Q6673Lt05KUExTtH9pmbKgjSu7aJXel1UnhaEphQrXiaVH1AzcOCV7Ry0Jk3v-cEBn74GFkYfXPB6b0EyEW7jTPUhyPHl9D_sx3tbcT752yV3VnfWwgxkeh2ji33_Zuu170Lw0MqlNwvlV5JguW4MmRpD3jVG4i92efT1Apqf-K4Tfu0_N7P5d-NBhoWyNvFNpW14FU3pScJYWfwAnWgRRA</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Alison, Jennifer A</creator><creator>Kenny, Patricia</creator><creator>King, Madeleine T</creator><creator>McKinley, Sharon</creator><creator>Aitken, Leanne M</creator><creator>Leslie, Gavin D</creator><creator>Elliott, Doug</creator><general>American Physical Therapy Association</general><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8GL</scope><scope>ISN</scope><scope>ISR</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>20121201</creationdate><title>Repeatability of the Six-Minute Walk Test and Relation to Physical Function in Survivors of a Critical Illness</title><author>Alison, Jennifer A ; 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However, the repeatability of the 6MWT performed at home in survivors of a critical illness has not been evaluated. The purpose of this study was to evaluate, in survivors of a critical illness: (1) the repeatability of the 6MWT performed at home, (2) the effect on estimates of change in functional exercise capacity if only one 6MWT was performed at follow-up assessments, and (3) the relationship between the physical functioning (PF) score of the 36-Item Short-Form Health Survey questionnaire (SF-36) and the 6MWT. Repeated measures of the 6MWT and SF-36 were obtained. Eligible participants had an intensive care unit (ICU) length of stay of ≥48 hours and were mechanically ventilated for ≥24 hours. Two 6MWTs and the SF-36 were conducted in participants' homes at weeks 1, 8, and 26 after hospital discharge. One hundred seventy-three participants completed the study. The participants had a mean age of 57 years (SD=16), a mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score on admission of 19 (SD=10), a mean ICU length of stay of 9 days (SD=8), and a mean mechanical ventilation time of 140 hours (SD=137). Of the 173 participants, 110 performed two 6MWTs at weeks 1, 8, and 26. There were significant mean increases in 6-minute walk distance in the second test of 15 m (P<.0001) at week 1, 13 m (P<.0001) at week 8, and 9 m (P=.04) at week 26. If only one 6MWT was performed at weeks 8 and 26, the estimate of change in 6-minute walk distance from week 1 was 19 m less (P<.001) at both weeks 8 and 26. There was a moderate to strong correlation between SF-36 PF score and 6-minute walk distance at each assessment (week 1: r=.62, P<.001; week 8: r=.55, P<.001; and week 26: r=.47, P<.001). Some study participants were unable to perform a second 6MWT, and these participants may have differed in important aspects of function compared with those individuals who completed two 6MWTs. In survivors of a critical illness, the 6MWT in the home environment should be performed twice at each assessment to give an accurate reflection of change in exercise capacity over time. The SF-36 PF score was a strong indicator of 6-minute walk distance in early recovery from a critical illness.]]></abstract><cop>United States</cop><pub>American Physical Therapy Association</pub><pmid>22577064</pmid><doi>10.2522/ptj.20110410</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Care and treatment
Confidence intervals
Critical Illness - rehabilitation
Critically ill
Critically ill persons
Disability Evaluation
Exercise Test
Exercise tests
Exercise Tolerance
Female
Follow-Up Studies
Health aspects
Home Care Services
Humans
Illnesses
Intensive Care Units
Male
Methods
Middle Aged
Older people
Outcome and process assessment (Health Care)
Outcome and process assessment (Medical care)
Outcome Assessment (Health Care) - methods
Rehabilitation
Reproducibility of Results
Respiration, Artificial
Studies
Survivors
title Repeatability of the Six-Minute Walk Test and Relation to Physical Function in Survivors of a Critical Illness
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