Macular lymphocytic arteritis: first clinical presentation with ulcers

Macular lymphocytic arteritis describes a recently reported entity, clinically characterized by asymptomatic hyperpigmented macules on the lower limbs, without association of systemic diseases. Histopathologically it is characterized by a lymphocytic arteritis with a hyalinized fibrin ring. We repor...

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Veröffentlicht in:Journal of cutaneous pathology 2013-04, Vol.40 (4), p.424-427
Hauptverfasser: Llamas‐Velasco, M., García‐Martín, P., Sánchez‐Pérez, J., Sotomayor, E., Fraga, J., García‐Diez, A.
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container_end_page 427
container_issue 4
container_start_page 424
container_title Journal of cutaneous pathology
container_volume 40
creator Llamas‐Velasco, M.
García‐Martín, P.
Sánchez‐Pérez, J.
Sotomayor, E.
Fraga, J.
García‐Diez, A.
description Macular lymphocytic arteritis describes a recently reported entity, clinically characterized by asymptomatic hyperpigmented macules on the lower limbs, without association of systemic diseases. Histopathologically it is characterized by a lymphocytic arteritis with a hyalinized fibrin ring. We report a new case presenting with ulceration, a finding not previously described. A 25‐year‐old Hispanic woman was evaluated for a 1‐year history of a gradually progressive, asymptomatic eruption that begins at level of both knees and progressively affects both legs and feet. She also referred recently appeared ulcers on inner right ankle without previous traumatism. Physical examination revealed multiple fairly well‐defined light brown and faint pink patches with petechiae on as well as retiform crusts and livedoid lesions on inner right ankle. Both types of lesions were biopsied showing lymphocytic arteritis with fibrinoid necrosis and thrombus. There were no relevant laboratory alterations. The clinical peculiarity of our case is the clinical image of the lesions mimicking a pigmented purpuric dermatosis and the presence of a non‐traumatic ulcer which could be explained because chronic lymphocytic damage may cause ischemic damage. Ulceration in our case supports consideration of macular arteritis as a latent form of cutaneous polyarteritis nodosa.
doi_str_mv 10.1111/cup.12094
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Histopathologically it is characterized by a lymphocytic arteritis with a hyalinized fibrin ring. We report a new case presenting with ulceration, a finding not previously described. A 25‐year‐old Hispanic woman was evaluated for a 1‐year history of a gradually progressive, asymptomatic eruption that begins at level of both knees and progressively affects both legs and feet. She also referred recently appeared ulcers on inner right ankle without previous traumatism. Physical examination revealed multiple fairly well‐defined light brown and faint pink patches with petechiae on as well as retiform crusts and livedoid lesions on inner right ankle. Both types of lesions were biopsied showing lymphocytic arteritis with fibrinoid necrosis and thrombus. There were no relevant laboratory alterations. 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subjects Adult
Ankle
Arteritis
Arteritis - pathology
Eruptions
Female
fibrin
Humans
Ischemia
Leg
Light effects
Limbs
Lymphocytes - pathology
macular lyphocytic arteritis
Mimicry
Necrosis
Pigmentation Disorders - pathology
pigmented purpuric eruption
Polyarteritis Nodosa - pathology
Purpura
Purpura - pathology
Skin - blood supply
Skin Diseases, Vascular - pathology
skin ulcer
Skin Ulcer - pathology
Thrombosis
Ulcers
title Macular lymphocytic arteritis: first clinical presentation with ulcers
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