Myocardial Infarction After Hip Fracture Repair: A Population-Based Study
Objectives To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1‐year mortality. Design A population‐based, historical cohort study of individuals who underwent surgical repair of a hip fra...
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| Veröffentlicht in: | Journal of the American Geriatrics Society (JAGS) 2012-11, Vol.60 (11), p.2020-2026 |
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| container_issue | 11 |
| container_start_page | 2020 |
| container_title | Journal of the American Geriatrics Society (JAGS) |
| container_volume | 60 |
| creator | Huddleston, Jeanne M. Gullerud, Rachel E. Smither, Fantley Huddleston, Paul M. Larson, Dirk R. Phy, Michael P. Melton III, L. Joseph Roger, Veronique L. |
| description | Objectives
To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1‐year mortality.
Design
A population‐based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project.
Setting
Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota.
Participants
Over the 15‐year study period (1988–2002), 1,116 elderly adults underwent surgical repair of a hip fracture.
Measurements
At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv‐MI), subclinical myocardial ischemia, and no myocardial ischemia. One‐year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv‐MI and 1‐year mortality.
Results
Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv‐MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1‐year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One‐year mortality for those with cv‐MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv‐MI, male sex, and history of heart failure or dementia were independently associated with greater 1‐year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective.
Conclusion
Rates of early postoperative, cv‐MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1‐year mortality. |
| doi_str_mv | 10.1111/j.1532-5415.2012.04205.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1328510587</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2814159301</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5485-6ff92168aca7d6a6efa9f6454d22f426571cc32483fa45fca8759930f020cab73</originalsourceid><addsrcrecordid>eNqN0Vtv0zAYBmALgVgZ_AUUCSFxk-BDfAgSF91Eu7INEBvj0vrm2JJLmgQ7Ee2_x6GlSFwtN47k5_XpRSgjuCDpe7suCGc05yXhBcWEFrikmBfbR2h2nHiMZhhjmitByhP0LMY1ThIr9RSdUEYIZoLO0Op61xkItYcmW7UOghl812ZzN9iQXfg-WwQwwxhs9tX24MO7bJ596fqxgcnlZxBtnd0MY717jp44aKJ9cRhP0bfFh9vzi_zq83J1Pr_KDS8Vz4VzFSVCgQFZCxDWQeVEycuaUldSwSUxhtFSMQcldwaU5FXFsMMUG7iX7BS92a_bh-7naOOgNz4a2zTQ2m6MmjCqOMFcPYASSZRIbzfRV__RdTeGNl0kKU6YlBWnSam9MqGLMVin--A3EHaaYD01o9d6KkBPBeipGf2nGb1N0ZeHDcb7ja2Pwb9VJPD6ACAaaFyA1vj4zwlRUUx5cu_37pdv7O7BB9AflzfTX8rn-7yPg90e8xB-aCGZ5Pr7p6WWd5eLy-vbO33GfgN0LLVD</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1151377952</pqid></control><display><type>article</type><title>Myocardial Infarction After Hip Fracture Repair: A Population-Based Study</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Huddleston, Jeanne M. ; Gullerud, Rachel E. ; Smither, Fantley ; Huddleston, Paul M. ; Larson, Dirk R. ; Phy, Michael P. ; Melton III, L. Joseph ; Roger, Veronique L.</creator><creatorcontrib>Huddleston, Jeanne M. ; Gullerud, Rachel E. ; Smither, Fantley ; Huddleston, Paul M. ; Larson, Dirk R. ; Phy, Michael P. ; Melton III, L. Joseph ; Roger, Veronique L.</creatorcontrib><description>Objectives
To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1‐year mortality.
Design
A population‐based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project.
Setting
Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota.
Participants
Over the 15‐year study period (1988–2002), 1,116 elderly adults underwent surgical repair of a hip fracture.
Measurements
At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv‐MI), subclinical myocardial ischemia, and no myocardial ischemia. One‐year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv‐MI and 1‐year mortality.
Results
Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv‐MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1‐year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One‐year mortality for those with cv‐MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv‐MI, male sex, and history of heart failure or dementia were independently associated with greater 1‐year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective.
Conclusion
Rates of early postoperative, cv‐MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1‐year mortality.</description><identifier>ISSN: 0002-8614</identifier><identifier>EISSN: 1532-5415</identifier><identifier>DOI: 10.1111/j.1532-5415.2012.04205.x</identifier><identifier>PMID: 23110362</identifier><identifier>CODEN: JAGSAF</identifier><language>eng</language><publisher>Hoboken, NJ: Blackwell Publishing Ltd</publisher><subject>Aged, 80 and over ; Biological and medical sciences ; Cardiology. Vascular system ; Coronary heart disease ; Dementia disorders ; Elderly ; Epidemiology ; Female ; General aspects ; geriatric ; Heart ; Heart attacks ; Hip fracture ; Hip Fractures - surgery ; Hip joint ; Historical account ; Hospitals ; Humans ; Male ; Medical sciences ; Miscellaneous ; Mortality ; Myocardial infarction ; Myocardial Infarction - epidemiology ; Myocardial Infarction - mortality ; Orthopedics ; postoperative complications ; Postoperative Complications - epidemiology ; Postoperative period ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk factors ; Surgery ; Survival Rate</subject><ispartof>Journal of the American Geriatrics Society (JAGS), 2012-11, Vol.60 (11), p.2020-2026</ispartof><rights>2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society</rights><rights>2014 INIST-CNRS</rights><rights>2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.</rights><rights>2012 American Geriatrics Society and Wiley Periodicals, Inc</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5485-6ff92168aca7d6a6efa9f6454d22f426571cc32483fa45fca8759930f020cab73</citedby><cites>FETCH-LOGICAL-c5485-6ff92168aca7d6a6efa9f6454d22f426571cc32483fa45fca8759930f020cab73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1532-5415.2012.04205.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1532-5415.2012.04205.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26692025$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23110362$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huddleston, Jeanne M.</creatorcontrib><creatorcontrib>Gullerud, Rachel E.</creatorcontrib><creatorcontrib>Smither, Fantley</creatorcontrib><creatorcontrib>Huddleston, Paul M.</creatorcontrib><creatorcontrib>Larson, Dirk R.</creatorcontrib><creatorcontrib>Phy, Michael P.</creatorcontrib><creatorcontrib>Melton III, L. Joseph</creatorcontrib><creatorcontrib>Roger, Veronique L.</creatorcontrib><title>Myocardial Infarction After Hip Fracture Repair: A Population-Based Study</title><title>Journal of the American Geriatrics Society (JAGS)</title><addtitle>J Am Geriatr Soc</addtitle><description>Objectives
To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1‐year mortality.
Design
A population‐based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project.
Setting
Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota.
Participants
Over the 15‐year study period (1988–2002), 1,116 elderly adults underwent surgical repair of a hip fracture.
Measurements
At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv‐MI), subclinical myocardial ischemia, and no myocardial ischemia. One‐year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv‐MI and 1‐year mortality.
Results
Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv‐MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1‐year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One‐year mortality for those with cv‐MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv‐MI, male sex, and history of heart failure or dementia were independently associated with greater 1‐year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective.
Conclusion
Rates of early postoperative, cv‐MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1‐year mortality.</description><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary heart disease</subject><subject>Dementia disorders</subject><subject>Elderly</subject><subject>Epidemiology</subject><subject>Female</subject><subject>General aspects</subject><subject>geriatric</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Hip fracture</subject><subject>Hip Fractures - surgery</subject><subject>Hip joint</subject><subject>Historical account</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Mortality</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Myocardial Infarction - mortality</subject><subject>Orthopedics</subject><subject>postoperative complications</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative period</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Risk factors</subject><subject>Surgery</subject><subject>Survival Rate</subject><issn>0002-8614</issn><issn>1532-5415</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0Vtv0zAYBmALgVgZ_AUUCSFxk-BDfAgSF91Eu7INEBvj0vrm2JJLmgQ7Ee2_x6GlSFwtN47k5_XpRSgjuCDpe7suCGc05yXhBcWEFrikmBfbR2h2nHiMZhhjmitByhP0LMY1ThIr9RSdUEYIZoLO0Op61xkItYcmW7UOghl812ZzN9iQXfg-WwQwwxhs9tX24MO7bJ596fqxgcnlZxBtnd0MY717jp44aKJ9cRhP0bfFh9vzi_zq83J1Pr_KDS8Vz4VzFSVCgQFZCxDWQeVEycuaUldSwSUxhtFSMQcldwaU5FXFsMMUG7iX7BS92a_bh-7naOOgNz4a2zTQ2m6MmjCqOMFcPYASSZRIbzfRV__RdTeGNl0kKU6YlBWnSam9MqGLMVin--A3EHaaYD01o9d6KkBPBeipGf2nGb1N0ZeHDcb7ja2Pwb9VJPD6ACAaaFyA1vj4zwlRUUx5cu_37pdv7O7BB9AflzfTX8rn-7yPg90e8xB-aCGZ5Pr7p6WWd5eLy-vbO33GfgN0LLVD</recordid><startdate>201211</startdate><enddate>201211</enddate><creator>Huddleston, Jeanne M.</creator><creator>Gullerud, Rachel E.</creator><creator>Smither, Fantley</creator><creator>Huddleston, Paul M.</creator><creator>Larson, Dirk R.</creator><creator>Phy, Michael P.</creator><creator>Melton III, L. Joseph</creator><creator>Roger, Veronique L.</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>201211</creationdate><title>Myocardial Infarction After Hip Fracture Repair: A Population-Based Study</title><author>Huddleston, Jeanne M. ; Gullerud, Rachel E. ; Smither, Fantley ; Huddleston, Paul M. ; Larson, Dirk R. ; Phy, Michael P. ; Melton III, L. Joseph ; Roger, Veronique L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5485-6ff92168aca7d6a6efa9f6454d22f426571cc32483fa45fca8759930f020cab73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary heart disease</topic><topic>Dementia disorders</topic><topic>Elderly</topic><topic>Epidemiology</topic><topic>Female</topic><topic>General aspects</topic><topic>geriatric</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Hip fracture</topic><topic>Hip Fractures - surgery</topic><topic>Hip joint</topic><topic>Historical account</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Mortality</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Myocardial Infarction - mortality</topic><topic>Orthopedics</topic><topic>postoperative complications</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative period</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Risk factors</topic><topic>Surgery</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huddleston, Jeanne M.</creatorcontrib><creatorcontrib>Gullerud, Rachel E.</creatorcontrib><creatorcontrib>Smither, Fantley</creatorcontrib><creatorcontrib>Huddleston, Paul M.</creatorcontrib><creatorcontrib>Larson, Dirk R.</creatorcontrib><creatorcontrib>Phy, Michael P.</creatorcontrib><creatorcontrib>Melton III, L. Joseph</creatorcontrib><creatorcontrib>Roger, Veronique L.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of the American Geriatrics Society (JAGS)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huddleston, Jeanne M.</au><au>Gullerud, Rachel E.</au><au>Smither, Fantley</au><au>Huddleston, Paul M.</au><au>Larson, Dirk R.</au><au>Phy, Michael P.</au><au>Melton III, L. Joseph</au><au>Roger, Veronique L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Myocardial Infarction After Hip Fracture Repair: A Population-Based Study</atitle><jtitle>Journal of the American Geriatrics Society (JAGS)</jtitle><addtitle>J Am Geriatr Soc</addtitle><date>2012-11</date><risdate>2012</risdate><volume>60</volume><issue>11</issue><spage>2020</spage><epage>2026</epage><pages>2020-2026</pages><issn>0002-8614</issn><eissn>1532-5415</eissn><coden>JAGSAF</coden><abstract>Objectives
To quantify the occurrence of myocardial infarction (MI) occurring in the early postoperative period after surgical hip fracture repair and estimate the effect on 1‐year mortality.
Design
A population‐based, historical cohort study of individuals who underwent surgical repair of a hip fracture that used the computerized medical record linkage system of the Rochester Epidemiology Project.
Setting
Academic and community hospitals, outpatient offices, and nursing homes in Olmsted County, Minnesota.
Participants
Over the 15‐year study period (1988–2002), 1,116 elderly adults underwent surgical repair of a hip fracture.
Measurements
At the end of the first 7 days after hip fracture repair, participants were classified into one of three groups: clinically verified MI (cv‐MI), subclinical myocardial ischemia, and no myocardial ischemia. One‐year mortality was compared between these groups. Multivariate models assessed risk factors for early postoperative cv‐MI and 1‐year mortality.
Results
Within the first 7 days after hip fracture repair, 116 (10.4%) participants experienced cv‐MI and 41 (3.7%) subclinical myocardial ischemia. Overall 1‐year mortality was 22%, with no difference between those with subclinical myocardial ischemia and those with no myocardial ischemia. One‐year mortality for those with cv‐MI (35.8%) was significantly higher than for the other two groups. Occurrence of early postoperative cv‐MI, male sex, and history of heart failure or dementia were independently associated with greater 1‐year mortality, whereas prefracture home residence and preoperative higher hemoglobin were protective.
Conclusion
Rates of early postoperative, cv‐MI after hip fracture repair exceed rates after other major orthopedic surgeries and are independently associated with greater 1‐year mortality.</abstract><cop>Hoboken, NJ</cop><pub>Blackwell Publishing Ltd</pub><pmid>23110362</pmid><doi>10.1111/j.1532-5415.2012.04205.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-8614 |
| ispartof | Journal of the American Geriatrics Society (JAGS), 2012-11, Vol.60 (11), p.2020-2026 |
| issn | 0002-8614 1532-5415 |
| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Aged, 80 and over Biological and medical sciences Cardiology. Vascular system Coronary heart disease Dementia disorders Elderly Epidemiology Female General aspects geriatric Heart Heart attacks Hip fracture Hip Fractures - surgery Hip joint Historical account Hospitals Humans Male Medical sciences Miscellaneous Mortality Myocardial infarction Myocardial Infarction - epidemiology Myocardial Infarction - mortality Orthopedics postoperative complications Postoperative Complications - epidemiology Postoperative period Public health. Hygiene Public health. Hygiene-occupational medicine Risk factors Surgery Survival Rate |
| title | Myocardial Infarction After Hip Fracture Repair: A Population-Based Study |
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