Digital Electrophoresis of Charged Droplets
A digital microfluidic system based on a direct electric charging and subsequent electrophoretic manipulation of droplets is made by simple fabrication at low cost. Digitally controlled two-dimensional droplet motions are realized by digital polarity control of an array of electrodes. By independent...
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Veröffentlicht in: | Analytical chemistry (Washington) 2013-04, Vol.85 (8), p.4038-4044 |
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creator | Im, Do Jin Yoo, Byeong Sun Ahn, Myung Mo Moon, Dustin Kang, In Seok |
description | A digital microfluidic system based on a direct electric charging and subsequent electrophoretic manipulation of droplets is made by simple fabrication at low cost. Digitally controlled two-dimensional droplet motions are realized by digital polarity control of an array of electrodes. By independent control of droplets and colorimetric detection, the coalescence and mixing of droplets is analyzed quantitatively. The gelation of sodium alginate and the crystallization of calcium carbonate by multiple droplet translations and coalescence and the actuation of glassy carbon beads are demonstrated to show the versatile manipulation capability of the proposed technology. Finally, we discuss the implications and potentials of the present technology. |
doi_str_mv | 10.1021/ac303778j |
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Digitally controlled two-dimensional droplet motions are realized by digital polarity control of an array of electrodes. By independent control of droplets and colorimetric detection, the coalescence and mixing of droplets is analyzed quantitatively. The gelation of sodium alginate and the crystallization of calcium carbonate by multiple droplet translations and coalescence and the actuation of glassy carbon beads are demonstrated to show the versatile manipulation capability of the proposed technology. Finally, we discuss the implications and potentials of the present technology.</description><identifier>ISSN: 0003-2700</identifier><identifier>EISSN: 1520-6882</identifier><identifier>DOI: 10.1021/ac303778j</identifier><identifier>PMID: 23489042</identifier><identifier>CODEN: ANCHAM</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Alginates - chemistry ; Analytical chemistry ; Buffers ; Calcium Carbonate - chemistry ; Charged particles ; Crystallization ; Electricity ; Electrocatalysis ; Electrodes ; Electrophoresis - economics ; Electrophoresis - instrumentation ; Electrophoresis - methods ; Gels ; Glucuronic Acid - chemistry ; Hexuronic Acids - chemistry ; Hydrodynamics ; Manipulation ; Microfluidic Analytical Techniques - economics ; Microfluidic Analytical Techniques - instrumentation ; Microfluidic Analytical Techniques - methods</subject><ispartof>Analytical chemistry (Washington), 2013-04, Vol.85 (8), p.4038-4044</ispartof><rights>Copyright © 2013 American Chemical Society</rights><rights>Copyright American Chemical Society Apr 16, 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a409t-72c08efc4e84f8d764c1c0e5715534ce9184820e9d06e2e5e22474b582b9b81a3</citedby><cites>FETCH-LOGICAL-a409t-72c08efc4e84f8d764c1c0e5715534ce9184820e9d06e2e5e22474b582b9b81a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/ac303778j$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/ac303778j$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2752,27053,27901,27902,56713,56763</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23489042$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Im, Do Jin</creatorcontrib><creatorcontrib>Yoo, Byeong Sun</creatorcontrib><creatorcontrib>Ahn, Myung Mo</creatorcontrib><creatorcontrib>Moon, Dustin</creatorcontrib><creatorcontrib>Kang, In Seok</creatorcontrib><title>Digital Electrophoresis of Charged Droplets</title><title>Analytical chemistry (Washington)</title><addtitle>Anal. 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Finally, we discuss the implications and potentials of the present technology.</description><subject>Alginates - chemistry</subject><subject>Analytical chemistry</subject><subject>Buffers</subject><subject>Calcium Carbonate - chemistry</subject><subject>Charged particles</subject><subject>Crystallization</subject><subject>Electricity</subject><subject>Electrocatalysis</subject><subject>Electrodes</subject><subject>Electrophoresis - economics</subject><subject>Electrophoresis - instrumentation</subject><subject>Electrophoresis - methods</subject><subject>Gels</subject><subject>Glucuronic Acid - chemistry</subject><subject>Hexuronic Acids - chemistry</subject><subject>Hydrodynamics</subject><subject>Manipulation</subject><subject>Microfluidic Analytical Techniques - economics</subject><subject>Microfluidic Analytical Techniques - instrumentation</subject><subject>Microfluidic Analytical Techniques - methods</subject><issn>0003-2700</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpl0F9LwzAUBfAgipvTB7-AFERQpHpzkybpo2zzDwx80eeSprdbR7fOpH3w29uxKaJPgcuPc8Jh7JzDHQfk99YJEFqb5QEb8gQhVsbgIRsCgIhRAwzYSQhLAM6Bq2M2QCFNChKH7HZSzavW1tG0Jtf6ZrNoPIUqRE0ZjRfWz6mIJv25pjacsqPS1oHO9u-IvT9O38bP8ez16WX8MIuthLSNNTowVDpJRpam0Eo67oASzZNESEcpN9IgUFqAIqSEEKWWeWIwT3PDrRix613uxjcfHYU2W1XBUV3bNTVdyLhAg6iUVj29_EOXTefX_e-2qm9KZF86Yjc75XwTgqcy2_hqZf1nxiHbLpj9LNjbi31il6-o-JHfk_XgagesC7_a_gV9AUyhdBE</recordid><startdate>20130416</startdate><enddate>20130416</enddate><creator>Im, Do Jin</creator><creator>Yoo, Byeong Sun</creator><creator>Ahn, Myung Mo</creator><creator>Moon, Dustin</creator><creator>Kang, In Seok</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7U5</scope><scope>7U7</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20130416</creationdate><title>Digital Electrophoresis of Charged Droplets</title><author>Im, Do Jin ; Yoo, Byeong Sun ; Ahn, Myung Mo ; Moon, Dustin ; Kang, In Seok</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a409t-72c08efc4e84f8d764c1c0e5715534ce9184820e9d06e2e5e22474b582b9b81a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Alginates - chemistry</topic><topic>Analytical chemistry</topic><topic>Buffers</topic><topic>Calcium Carbonate - chemistry</topic><topic>Charged particles</topic><topic>Crystallization</topic><topic>Electricity</topic><topic>Electrocatalysis</topic><topic>Electrodes</topic><topic>Electrophoresis - economics</topic><topic>Electrophoresis - instrumentation</topic><topic>Electrophoresis - methods</topic><topic>Gels</topic><topic>Glucuronic Acid - chemistry</topic><topic>Hexuronic Acids - chemistry</topic><topic>Hydrodynamics</topic><topic>Manipulation</topic><topic>Microfluidic Analytical Techniques - economics</topic><topic>Microfluidic Analytical Techniques - instrumentation</topic><topic>Microfluidic Analytical Techniques - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Im, Do Jin</creatorcontrib><creatorcontrib>Yoo, Byeong Sun</creatorcontrib><creatorcontrib>Ahn, Myung Mo</creatorcontrib><creatorcontrib>Moon, Dustin</creatorcontrib><creatorcontrib>Kang, In Seok</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Analytical chemistry (Washington)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Im, Do Jin</au><au>Yoo, Byeong Sun</au><au>Ahn, Myung Mo</au><au>Moon, Dustin</au><au>Kang, In Seok</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Digital Electrophoresis of Charged Droplets</atitle><jtitle>Analytical chemistry (Washington)</jtitle><addtitle>Anal. 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subjects | Alginates - chemistry Analytical chemistry Buffers Calcium Carbonate - chemistry Charged particles Crystallization Electricity Electrocatalysis Electrodes Electrophoresis - economics Electrophoresis - instrumentation Electrophoresis - methods Gels Glucuronic Acid - chemistry Hexuronic Acids - chemistry Hydrodynamics Manipulation Microfluidic Analytical Techniques - economics Microfluidic Analytical Techniques - instrumentation Microfluidic Analytical Techniques - methods |
title | Digital Electrophoresis of Charged Droplets |
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