Atorvastatin: an efficient step forward in mesenchymal stem cell therapy of diabetic retinopathy

Abstract Diabetic retinopathy (DR), a leading cause of vision loss and a significant source of morbidity, is the most common ocular complication of prolonged diabetes mellitus. Most therapeutic approaches address DR by preventing or destroying neovasculature; however, this fails to eliminate pathoge...

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Veröffentlicht in:	Cytotherapy (Oxford, England) England), 2013-03, Vol.15 (3), p.263-266
Hauptverfasser:	Mottaghi, Sayeh, Larijani, Bagher, Sharifi, Ali M
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals atorvastatin Atorvastatin Calcium diabetic retinopathy Diabetic Retinopathy - pathology Diabetic Retinopathy - therapy Gene Expression Regulation Genetic Therapy Heptanoic Acids - administration & dosage Humans Mesenchymal Stem Cell Transplantation mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Nitric Oxide - metabolism Nitric Oxide Synthase Type III Other Pyrroles - administration & dosage Rats Receptors, CXCR4 - metabolism vascular endothelial growth factor Vascular Endothelial Growth Factor A - antagonists & inhibitors Vascular Endothelial Growth Factor A - metabolism
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