Complexities of Crumbs Function and Regulation in Tissue Morphogenesis

Establishing and maintaining epithelial polarity is crucial during development and for adult tissue homeostasis. A complex network of evolutionarily conserved proteins regulates this compartmentalization. One such protein is Crumbs, a type I transmembrane protein initially shown to be an important a...

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Veröffentlicht in:	Current biology 2013-04, Vol.23 (7), p.R289-R293
Hauptverfasser:	Pocha, Shirin Meher, Knust, Elisabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anisotropy Dimerization Drosophila Drosophila Proteins - genetics Epithelium - physiology Gene Expression Regulation, Developmental - genetics Humans Membrane Proteins - genetics Models, Biological Morphogenesis - genetics Morphogenesis - physiology Multigene Family - genetics Protein Structure, Tertiary Retina - metabolism Species Specificity Zebrafish
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