Patients’ Choice on Axillary Lymph Node Dissection Following Sentinel Lymph Node Micrometastasis — First Report on Prospective Use of a Nomogram in Very Low Risk Patients

The optimal locoregional treatment of patients diagnosed with sentinel node (SN) micrometastasis is controversial. A previously reported and validated nomogram was used to calculate the risk of non-SN metastasis in patients with SN micrometastasis over a period of 2 years. Patients were given detail...

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Veröffentlicht in:Pathology oncology research 2013-04, Vol.19 (2), p.211-216
Hauptverfasser: Cserni, Gábor, Bezsenyi, Istvánné, Markó, László
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container_title Pathology oncology research
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creator Cserni, Gábor
Bezsenyi, Istvánné
Markó, László
description The optimal locoregional treatment of patients diagnosed with sentinel node (SN) micrometastasis is controversial. A previously reported and validated nomogram was used to calculate the risk of non-SN metastasis in patients with SN micrometastasis over a period of 2 years. Patients were given detailed information about the risk, consequences and treatment options of non-SN involvement, the risk and potential complications of unnecessary completion axillary lymph node dissection (ALND), the imperfectness of the nomogram, and other factors that may influence their selection of further treatment. They also received a questionnaire to monitor factors influencing their decisions. Of the 25 patients participating in the study, 10 have opted for ALND. The only factor that seemed to influence their choice was fear from disease recurrence. Giving detailed information to SN micrometastatic patients is a patient-centered alternative to current recommendations on performing ALND in all such patients or omitting ALND in all of them.
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subjects Adult
Aged
Axilla
Biomedical and Life Sciences
Biomedicine
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Cancer Research
Choice Behavior
Female
Humans
Immunology
Lymph Node Excision - methods
Lymph Nodes - pathology
Lymph Nodes - surgery
Lymphatic Metastasis - pathology
Middle Aged
Neoplasm Micrometastasis
Nomograms
Oncology
Pathology
Prospective Studies
Sentinel Lymph Node Biopsy - methods
title Patients’ Choice on Axillary Lymph Node Dissection Following Sentinel Lymph Node Micrometastasis — First Report on Prospective Use of a Nomogram in Very Low Risk Patients
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