Total Synthesis of (−)-α-Kainic acid via Chirality Transfer through Ireland–Claisen Rearrangement

Total Synthesis of (−)-α-Kainic acid via Chirality Transfer through Ireland–Claisen Rearrangement

The total synthesis of (−)-α- Kainic acid is accomplished using a linear strategy involving Noyori asymmetric reduction and chirality transfer through Ireland–Claisen rearrangement as key steps.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of organic chemistry 2013-04, Vol.78 (7), p.3355-3360
Hauptverfasser: Kesava Reddy, Naredla, Chandrasekhar, Srivari
Format: Artikel
Sprache:eng
Schlagworte:
Kainic Acid - chemical synthesis
Kainic Acid - chemistry
Molecular Structure
Stereoisomerism
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The total synthesis of (−)-α- Kainic acid is accomplished using a linear strategy involving Noyori asymmetric reduction and chirality transfer through Ireland–Claisen rearrangement as key steps.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo400001t