Extent of peritumoral brain edema correlates with prognosis, tumoral growth pattern, HIF1a expression and angiogenic activity in patients with single brain metastases

To analyze the prognostic value of the extent of peritumoral brain edema in patients operated for single brain metastases (BM), we retrospectively evaluated pre-operative magnetic resonance images in a discovery cohort of 129 patients and a validation cohort of 118 patients, who underwent neurosurgi...

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Veröffentlicht in:	Clinical & experimental metastasis 2013-04, Vol.30 (4), p.357-368
Hauptverfasser:	Spanberger, Thomas, Berghoff, Anna S., Dinhof, Carina, Ilhan-Mutlu, Aysegül, Magerle, Manuel, Hutterer, Markus, Pichler, Josef, Wöhrer, Adelheid, Hackl, Monika, Widhalm, Georg, Hainfellner, Johannes A., Dieckmann, Karin, Marosi, Christine, Birner, Peter, Prayer, Daniela, Preusser, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Austria - epidemiology Biomedical and Life Sciences Biomedicine Brain Edema - epidemiology Brain Edema - metabolism Brain Edema - mortality Brain Neoplasms - metabolism Brain Neoplasms - mortality Brain Neoplasms - secondary Cancer Research Female Follow-Up Studies Hematology Humans Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Immunoenzyme Techniques Magnetic Resonance Imaging Male Middle Aged Neoplasms - metabolism Neoplasms - mortality Neoplasms - pathology Neovascularization, Pathologic - mortality Neuroimaging Oncology Prognosis Research Paper Retrospective Studies Surgical Oncology Survival Rate
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