Recombinant Fc-IL-18BPc isoform inhibits IL-18-induced cytokine production

IL-18 is a pro-inflammatory cytokine that is produced from T cells and NK cells. IL-18 has been implicated in the pathogenesis of various inflammatory and cardiovascular diseases. IL-18 binding protein (IL-18BP) is a natural inhibitor of IL-18 that possesses higher affinity to IL-18 than that of the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hybridoma (2005) 2012-04, Vol.31 (2), p.99-104
Hauptverfasser:	Hong, Kwangwon, Oh, Kwangjun, Lee, Siyoung, Hong, Jaewoo, Choi, Jida, Kwak, Areum, Kang, Dongjun, Kim, Eunsom, Jo, Seunghyun, Jhun, Hyunjhung, Kim, Soohyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiovascular diseases Cell Line Cell surface CHO Cells Cloning, Molecular Cricetinae Enzymes Humans Immunoglobulin Fc Fragments - biosynthesis Immunoglobulin Fc Fragments - genetics Immunoglobulin Fc Fragments - pharmacology Immunoglobulins Inflammation Inflammatory diseases Intercellular Signaling Peptides and Proteins - biosynthesis Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - pharmacology Interferon-gamma - biosynthesis Interferon-gamma - metabolism Interleukin 18 Interleukin 18 receptors Interleukin 6 Interleukin-18 - antagonists & inhibitors Interleukin-18 - metabolism Interleukin-6 - metabolism Lymphocytes T Natural killer cells Peripheral blood mononuclear cells Protein Isoforms Recombinant Fusion Proteins - biosynthesis Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - isolation & purification Recombinant Fusion Proteins - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!