Clonal transmission of a rare methicillin-resistant Staphylococcus aureus genotype between horses and staff at a veterinary teaching hospital

Methicillin-resistant Staphylococcus aureus (MRSA) infection or colonization has become a serious emerging condition in equine hospitals. Following the detection of MRSA in asymptomatic hospitalized horses and in two horses with post-operative wound infections, an investigation was conducted. Twelve...

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Veröffentlicht in:Veterinary microbiology 2013-03, Vol.162 (2-4), p.907-911
Hauptverfasser: Schwaber, Mitchell J., Navon-Venezia, Shiri, Masarwa, Samira, Tirosh-Levy, Sharon, Adler, Amos, Chmelnitsky, Inna, Carmeli, Yehuda, Klement, Eyal, Steinman, Amir
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container_end_page 911
container_issue 2-4
container_start_page 907
container_title Veterinary microbiology
container_volume 162
creator Schwaber, Mitchell J.
Navon-Venezia, Shiri
Masarwa, Samira
Tirosh-Levy, Sharon
Adler, Amos
Chmelnitsky, Inna
Carmeli, Yehuda
Klement, Eyal
Steinman, Amir
description Methicillin-resistant Staphylococcus aureus (MRSA) infection or colonization has become a serious emerging condition in equine hospitals. Following the detection of MRSA in asymptomatic hospitalized horses and in two horses with post-operative wound infections, an investigation was conducted. Twelve of 84 horses (14.3%) and 16 of 139 personnel (11.5%) were MRSA carriers. The profile of the dominant MRSA strain common to horses and staff was multi-drug-resistant, spa-type t535, SCCmec type V, pvl-negative. MLST of a representative isolate yielded sequence type (ST) 5. The risk of MRSA carriage among veterinary personnel was greater in equine veterinarians and full-time technicians in comparison to part-time technicians and to other personnel not working with horses. Strict infection control measures were implemented, horses infected or colonized with MRSA were isolated and decolonization of personnel was attempted. Six months after the intervention, the large animal department personnel and hospitalized horses were all MRSA-negative and the decolonization was considered successful. This outbreak, caused by a rare MRSA strain and involving both hospitalized horses and personnel, further demonstrates the ability of MRSA to spread between animals and humans and emphasizes the importance of infection control measures to decrease the risk for MRSA colonization and infection of both horses and personnel.
doi_str_mv 10.1016/j.vetmic.2012.11.020
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subjects Animals
Carrier State - veterinary
Disease Outbreaks - veterinary
Equine
Genotype
Horse Diseases - epidemiology
Horse Diseases - microbiology
Horse Diseases - transmission
Horses
Hospitals, Animal
Hospitals, Teaching
Humans
Infection control
Intervention
Israel - epidemiology
Methicillin-resistant Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus - genetics
Methicillin-Resistant Staphylococcus aureus - pathogenicity
Multilocus Sequence Typing
Outbreak
Staphylococcal Infections - epidemiology
Staphylococcal Infections - genetics
Staphylococcal Infections - transmission
Staphylococcal Infections - veterinary
Staphylococcus aureus
Veterinarians
Zoonoses - epidemiology
Zoonoses - microbiology
Zoonoses - transmission
Zoonosis
title Clonal transmission of a rare methicillin-resistant Staphylococcus aureus genotype between horses and staff at a veterinary teaching hospital
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