Anxiolytic Properties of New Chemical Entity, 5TIO1

2-[(2,6-dichlorobenzylidene)amino]-5,6-dihydro-4 H -cyclopenta[ b ]thiophene-3-carbonitrile), 5TIO1, is a new 2-aminothiophene derivative with a promising pharmacological activity. The aim of this work was to evaluate the potential anxiolytic effect of 5TIO1 in animal models. In the elevated plus-ma...

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Veröffentlicht in:	Neurochemical research 2013-04, Vol.38 (4), p.726-731
Hauptverfasser:	Fortes, Amanda C., Almeida, Antonia Amanda C., Mendonça-Júnior, Francisco Jaime B., Freitas, Rivelilson M., Soares-Sobrinho, José Lamartine, de La Roca Soares, Monica Felts
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Anti-Anxiety Agents - pharmacology Behavior, Animal - drug effects Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Exploratory Behavior - drug effects Maze Learning - drug effects Mice Neurochemistry Neurology Neurosciences Original Paper Receptors, GABA-A - drug effects Schiff Bases - pharmacology Thiophenes - pharmacology
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