Different Critical Perinatal Periods and Hypothalamic Sites of Oestradiol Action in the Defeminisation of Luteinising Hormone Surge and Lordosis Capacity in the Rat

Female rats show a gonadotrophin‐releasing hormone (GnRH)/luteinising hormone (LH) surge in the presence of a preovulatory level of oestrogen, whereas males do not because of brain defeminisation during the developmental period by perinatal oestrogen converted from androgen. The present study aimed...

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Veröffentlicht in:	Journal of neuroendocrinology 2013-03, Vol.25 (3), p.251-259
Hauptverfasser:	Sakakibara, M., Deura, C., Minabe, S., Iwata, Y., Uenoyama, Y., Maeda, K.-I., Tsukamura, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn AVPV Biological and medical sciences Brain Castration Critical period Developmental stages Estradiol - physiology Estrogens Female Fundamental and applied biological sciences. Psychology Glutamic acid receptors (ionotropic) Gonadotropin-releasing hormone Hormones Hypothalamus Hypothalamus (anterior) Hypothalamus - physiopathology lordosis Lordosis - physiopathology Luteinizing hormone Luteinizing Hormone - secretion Male Mammalian female genital system Morphology. Physiology N-Methyl-D-aspartic acid receptors Neonates Neurotransmitters Periventricular nucleus Pituitary (anterior) Postpartum Preoptic area Rats Rats, Wistar Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Sexual behavior Sexual Behavior, Animal sexual differentiation Vertebrates: reproduction
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