Quantitative assessment of neurochemical changes in a rat model of long-term alcohol consumption as detected by in vivo and ex vivo proton nuclear magnetic resonance spectroscopy

► We quantitatively assessed neurochemical profile of long-term alcohol exposed rats. ► We present first measurements of in vivo and ex vivo data in frontal cortex of rats. ► Myo-inositol and choline-compound levels were statistically altered in rat brain. ► Altered neurochemical profile provides us...

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Veröffentlicht in:	Neurochemistry international 2013-03, Vol.62 (4), p.502-509
Hauptverfasser:	Lee, Do-Wan, Kim, Sang-Young, Kim, Jae-Hwa, Lee, Taehyeong, Yoo, Changbum, Nam, Yoon-Ki, Jung, Jin-Young, Shin, Hae-Chung, Kim, Hwi-Yool, Kim, Dai-Jin, Choe, Bo-Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking Animals Astrocytes Ethanol Frontal cortex High-resolution In Vitro Techniques Magic angle spinning Magnetic Resonance Spectroscopy - methods Male Metabolism Models, Animal Protons Rats Rats, Sprague-Dawley
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