Peach allergy in spanish children: tolerance to the pulp and molecular sensitization profile
Background Peach allergy is the main cause of vegetable food allergy in the Mediterranean area. Pru p 3 is the major allergen, and it is mainly found in the peel. Objective We sought to calculate the frequency of tolerance to peach pulp in Spanish children suffering from allergic reactions after eat...
Gespeichert in:
| Veröffentlicht in: | Pediatric allergy and immunology 2013-03, Vol.24 (2), p.168-172 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 172 |
|---|---|
| container_issue | 2 |
| container_start_page | 168 |
| container_title | Pediatric allergy and immunology |
| container_volume | 24 |
| creator | Boyano-Martínez, Teresa Pedrosa, María Belver, Teresa Quirce, Santiago García-Ara, Carmen |
| description | Background
Peach allergy is the main cause of vegetable food allergy in the Mediterranean area. Pru p 3 is the major allergen, and it is mainly found in the peel.
Objective
We sought to calculate the frequency of tolerance to peach pulp in Spanish children suffering from allergic reactions after eating or having contact with peach and to analyze the sensitization pattern to peach allergens.
Methods
Fifty‐seven children (32 boys; median age, 7.4 yr) were included in the study. A systematized questionnaire on allergic reactions to peach was administered. Prick tests with peach peel and pulp, peach lipid transfer protein (LTP), and profilin were performed. Serum‐specific IgE to peach, rPru p 1, rPru p 3, and rPru p 4 was determined by ImmunoCAP. Oral food challenges (OFCs) with peach pulp were performed on all but one child.
Results
Eighty‐eight percent of the children had positive prick tests with peach peel, 35% with peach pulp, 88% with peach LTP, and 9% with profilin. Serum‐specific IgE to peach was demonstrated in 100% of the patients; rPru p 3‐specific IgE in 96%; rPru p 1‐specific IgE in 11%; and rPru p 4‐specific IgE in 10%. Oral food challenge was negative in 52 (93%) children.
Conclusions
More than 90% of the study population tolerated peeled peach. Pru p 3 was the major allergen. Pru p 1 and 4 showed low prevalence. |
| doi_str_mv | 10.1111/pai.12037 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1323807056</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1323807056</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4907-6c74df1e5e9d7fee6ab70ddfbcf2d2d74867de2f5b8485ac244f9328fa54588b3</originalsourceid><addsrcrecordid>eNqNkd9rFDEQx4Mo9nr64D8gAV_sw7b5naxvpWqtlNqCIogQcsnES93bXZNd9PzrjV7bB0FwXmZgPvMdZr4IPaHkkNY4Gl06pIxwfQ8tKG_bhhNu7qMFaYlsFJV6D-2Xck0I1VzRh2iPcUkUa-kCfb4E59fYdR3kL1ucelxG16eyxn6dupChf4GnoTZd76FWeFoDHuduxK4PeFM7fu5cxgX6kqb0001p6PGYh5g6eIQeRNcVeHyTl-jD61fvT9405-9Oz06OzxsvWqIb5bUIkYKENugIoNxKkxDiykcWWNDCKB2ARbkywkjnmRCx5cxEJ4U0ZsWX6PlOt-79NkOZ7CYVD13nehjmYiln3BBNpPoPlBrSqtaYij77C70e5tzXQywVXFChVf3nEh3sKJ-HUjJEO-a0cXlrKbG_3bHVHfvHnco-vVGcVxsId-StHRU42gHf6_e2_1ayl8dnt5LNbiKVCX7cTbj81SrNtbQfL07tW0Y_XV3xl_aC_wKsgqgS</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1434147617</pqid></control><display><type>article</type><title>Peach allergy in spanish children: tolerance to the pulp and molecular sensitization profile</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Boyano-Martínez, Teresa ; Pedrosa, María ; Belver, Teresa ; Quirce, Santiago ; García-Ara, Carmen</creator><creatorcontrib>Boyano-Martínez, Teresa ; Pedrosa, María ; Belver, Teresa ; Quirce, Santiago ; García-Ara, Carmen</creatorcontrib><description>Background
Peach allergy is the main cause of vegetable food allergy in the Mediterranean area. Pru p 3 is the major allergen, and it is mainly found in the peel.
Objective
We sought to calculate the frequency of tolerance to peach pulp in Spanish children suffering from allergic reactions after eating or having contact with peach and to analyze the sensitization pattern to peach allergens.
Methods
Fifty‐seven children (32 boys; median age, 7.4 yr) were included in the study. A systematized questionnaire on allergic reactions to peach was administered. Prick tests with peach peel and pulp, peach lipid transfer protein (LTP), and profilin were performed. Serum‐specific IgE to peach, rPru p 1, rPru p 3, and rPru p 4 was determined by ImmunoCAP. Oral food challenges (OFCs) with peach pulp were performed on all but one child.
Results
Eighty‐eight percent of the children had positive prick tests with peach peel, 35% with peach pulp, 88% with peach LTP, and 9% with profilin. Serum‐specific IgE to peach was demonstrated in 100% of the patients; rPru p 3‐specific IgE in 96%; rPru p 1‐specific IgE in 11%; and rPru p 4‐specific IgE in 10%. Oral food challenge was negative in 52 (93%) children.
Conclusions
More than 90% of the study population tolerated peeled peach. Pru p 3 was the major allergen. Pru p 1 and 4 showed low prevalence.</description><identifier>ISSN: 0905-6157</identifier><identifier>EISSN: 1399-3038</identifier><identifier>DOI: 10.1111/pai.12037</identifier><identifier>PMID: 23506291</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Allergens ; Antigens, Plant - immunology ; Biomarkers - blood ; Carrier Proteins - immunology ; Child ; Child, Preschool ; Children ; Cross-Sectional Studies ; Double-Blind Method ; Female ; Food hypersensitivity ; Food Hypersensitivity - blood ; Food Hypersensitivity - diagnosis ; Food Hypersensitivity - immunology ; Fruit - immunology ; Humans ; Hypersensitivity ; Immune Tolerance ; Immunoglobulin E ; Immunoglobulin E - blood ; Immunological tolerance ; Intradermal Tests ; Long-term potentiation ; Male ; molecular profiles ; peach allergy ; peach LTP ; Plant Proteins - immunology ; Population studies ; profilin ; Profilins - immunology ; Prospective Studies ; Prunus ; Prunus - immunology ; Pulp ; Spain ; Surveys and Questionnaires ; tolerance to peach pulp ; Vegetables</subject><ispartof>Pediatric allergy and immunology, 2013-03, Vol.24 (2), p.168-172</ispartof><rights>2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd</rights><rights>2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.</rights><rights>2013 John Wiley & Sons A/S</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4907-6c74df1e5e9d7fee6ab70ddfbcf2d2d74867de2f5b8485ac244f9328fa54588b3</citedby><cites>FETCH-LOGICAL-c4907-6c74df1e5e9d7fee6ab70ddfbcf2d2d74867de2f5b8485ac244f9328fa54588b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fpai.12037$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fpai.12037$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27922,27923,45572,45573</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23506291$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boyano-Martínez, Teresa</creatorcontrib><creatorcontrib>Pedrosa, María</creatorcontrib><creatorcontrib>Belver, Teresa</creatorcontrib><creatorcontrib>Quirce, Santiago</creatorcontrib><creatorcontrib>García-Ara, Carmen</creatorcontrib><title>Peach allergy in spanish children: tolerance to the pulp and molecular sensitization profile</title><title>Pediatric allergy and immunology</title><addtitle>Pediatr Allergy Immunol</addtitle><description>Background
Peach allergy is the main cause of vegetable food allergy in the Mediterranean area. Pru p 3 is the major allergen, and it is mainly found in the peel.
Objective
We sought to calculate the frequency of tolerance to peach pulp in Spanish children suffering from allergic reactions after eating or having contact with peach and to analyze the sensitization pattern to peach allergens.
Methods
Fifty‐seven children (32 boys; median age, 7.4 yr) were included in the study. A systematized questionnaire on allergic reactions to peach was administered. Prick tests with peach peel and pulp, peach lipid transfer protein (LTP), and profilin were performed. Serum‐specific IgE to peach, rPru p 1, rPru p 3, and rPru p 4 was determined by ImmunoCAP. Oral food challenges (OFCs) with peach pulp were performed on all but one child.
Results
Eighty‐eight percent of the children had positive prick tests with peach peel, 35% with peach pulp, 88% with peach LTP, and 9% with profilin. Serum‐specific IgE to peach was demonstrated in 100% of the patients; rPru p 3‐specific IgE in 96%; rPru p 1‐specific IgE in 11%; and rPru p 4‐specific IgE in 10%. Oral food challenge was negative in 52 (93%) children.
Conclusions
More than 90% of the study population tolerated peeled peach. Pru p 3 was the major allergen. Pru p 1 and 4 showed low prevalence.</description><subject>Adolescent</subject><subject>Allergens</subject><subject>Antigens, Plant - immunology</subject><subject>Biomarkers - blood</subject><subject>Carrier Proteins - immunology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Cross-Sectional Studies</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Food hypersensitivity</subject><subject>Food Hypersensitivity - blood</subject><subject>Food Hypersensitivity - diagnosis</subject><subject>Food Hypersensitivity - immunology</subject><subject>Fruit - immunology</subject><subject>Humans</subject><subject>Hypersensitivity</subject><subject>Immune Tolerance</subject><subject>Immunoglobulin E</subject><subject>Immunoglobulin E - blood</subject><subject>Immunological tolerance</subject><subject>Intradermal Tests</subject><subject>Long-term potentiation</subject><subject>Male</subject><subject>molecular profiles</subject><subject>peach allergy</subject><subject>peach LTP</subject><subject>Plant Proteins - immunology</subject><subject>Population studies</subject><subject>profilin</subject><subject>Profilins - immunology</subject><subject>Prospective Studies</subject><subject>Prunus</subject><subject>Prunus - immunology</subject><subject>Pulp</subject><subject>Spain</subject><subject>Surveys and Questionnaires</subject><subject>tolerance to peach pulp</subject><subject>Vegetables</subject><issn>0905-6157</issn><issn>1399-3038</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkd9rFDEQx4Mo9nr64D8gAV_sw7b5naxvpWqtlNqCIogQcsnES93bXZNd9PzrjV7bB0FwXmZgPvMdZr4IPaHkkNY4Gl06pIxwfQ8tKG_bhhNu7qMFaYlsFJV6D-2Xck0I1VzRh2iPcUkUa-kCfb4E59fYdR3kL1ucelxG16eyxn6dupChf4GnoTZd76FWeFoDHuduxK4PeFM7fu5cxgX6kqb0001p6PGYh5g6eIQeRNcVeHyTl-jD61fvT9405-9Oz06OzxsvWqIb5bUIkYKENugIoNxKkxDiykcWWNDCKB2ARbkywkjnmRCx5cxEJ4U0ZsWX6PlOt-79NkOZ7CYVD13nehjmYiln3BBNpPoPlBrSqtaYij77C70e5tzXQywVXFChVf3nEh3sKJ-HUjJEO-a0cXlrKbG_3bHVHfvHnco-vVGcVxsId-StHRU42gHf6_e2_1ayl8dnt5LNbiKVCX7cTbj81SrNtbQfL07tW0Y_XV3xl_aC_wKsgqgS</recordid><startdate>201303</startdate><enddate>201303</enddate><creator>Boyano-Martínez, Teresa</creator><creator>Pedrosa, María</creator><creator>Belver, Teresa</creator><creator>Quirce, Santiago</creator><creator>García-Ara, Carmen</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201303</creationdate><title>Peach allergy in spanish children: tolerance to the pulp and molecular sensitization profile</title><author>Boyano-Martínez, Teresa ; Pedrosa, María ; Belver, Teresa ; Quirce, Santiago ; García-Ara, Carmen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4907-6c74df1e5e9d7fee6ab70ddfbcf2d2d74867de2f5b8485ac244f9328fa54588b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Allergens</topic><topic>Antigens, Plant - immunology</topic><topic>Biomarkers - blood</topic><topic>Carrier Proteins - immunology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Cross-Sectional Studies</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Food hypersensitivity</topic><topic>Food Hypersensitivity - blood</topic><topic>Food Hypersensitivity - diagnosis</topic><topic>Food Hypersensitivity - immunology</topic><topic>Fruit - immunology</topic><topic>Humans</topic><topic>Hypersensitivity</topic><topic>Immune Tolerance</topic><topic>Immunoglobulin E</topic><topic>Immunoglobulin E - blood</topic><topic>Immunological tolerance</topic><topic>Intradermal Tests</topic><topic>Long-term potentiation</topic><topic>Male</topic><topic>molecular profiles</topic><topic>peach allergy</topic><topic>peach LTP</topic><topic>Plant Proteins - immunology</topic><topic>Population studies</topic><topic>profilin</topic><topic>Profilins - immunology</topic><topic>Prospective Studies</topic><topic>Prunus</topic><topic>Prunus - immunology</topic><topic>Pulp</topic><topic>Spain</topic><topic>Surveys and Questionnaires</topic><topic>tolerance to peach pulp</topic><topic>Vegetables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boyano-Martínez, Teresa</creatorcontrib><creatorcontrib>Pedrosa, María</creatorcontrib><creatorcontrib>Belver, Teresa</creatorcontrib><creatorcontrib>Quirce, Santiago</creatorcontrib><creatorcontrib>García-Ara, Carmen</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric allergy and immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boyano-Martínez, Teresa</au><au>Pedrosa, María</au><au>Belver, Teresa</au><au>Quirce, Santiago</au><au>García-Ara, Carmen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Peach allergy in spanish children: tolerance to the pulp and molecular sensitization profile</atitle><jtitle>Pediatric allergy and immunology</jtitle><addtitle>Pediatr Allergy Immunol</addtitle><date>2013-03</date><risdate>2013</risdate><volume>24</volume><issue>2</issue><spage>168</spage><epage>172</epage><pages>168-172</pages><issn>0905-6157</issn><eissn>1399-3038</eissn><abstract>Background
Peach allergy is the main cause of vegetable food allergy in the Mediterranean area. Pru p 3 is the major allergen, and it is mainly found in the peel.
Objective
We sought to calculate the frequency of tolerance to peach pulp in Spanish children suffering from allergic reactions after eating or having contact with peach and to analyze the sensitization pattern to peach allergens.
Methods
Fifty‐seven children (32 boys; median age, 7.4 yr) were included in the study. A systematized questionnaire on allergic reactions to peach was administered. Prick tests with peach peel and pulp, peach lipid transfer protein (LTP), and profilin were performed. Serum‐specific IgE to peach, rPru p 1, rPru p 3, and rPru p 4 was determined by ImmunoCAP. Oral food challenges (OFCs) with peach pulp were performed on all but one child.
Results
Eighty‐eight percent of the children had positive prick tests with peach peel, 35% with peach pulp, 88% with peach LTP, and 9% with profilin. Serum‐specific IgE to peach was demonstrated in 100% of the patients; rPru p 3‐specific IgE in 96%; rPru p 1‐specific IgE in 11%; and rPru p 4‐specific IgE in 10%. Oral food challenge was negative in 52 (93%) children.
Conclusions
More than 90% of the study population tolerated peeled peach. Pru p 3 was the major allergen. Pru p 1 and 4 showed low prevalence.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>23506291</pmid><doi>10.1111/pai.12037</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0905-6157 |
| ispartof | Pediatric allergy and immunology, 2013-03, Vol.24 (2), p.168-172 |
| issn | 0905-6157 1399-3038 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1323807056 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Allergens Antigens, Plant - immunology Biomarkers - blood Carrier Proteins - immunology Child Child, Preschool Children Cross-Sectional Studies Double-Blind Method Female Food hypersensitivity Food Hypersensitivity - blood Food Hypersensitivity - diagnosis Food Hypersensitivity - immunology Fruit - immunology Humans Hypersensitivity Immune Tolerance Immunoglobulin E Immunoglobulin E - blood Immunological tolerance Intradermal Tests Long-term potentiation Male molecular profiles peach allergy peach LTP Plant Proteins - immunology Population studies profilin Profilins - immunology Prospective Studies Prunus Prunus - immunology Pulp Spain Surveys and Questionnaires tolerance to peach pulp Vegetables |
| title | Peach allergy in spanish children: tolerance to the pulp and molecular sensitization profile |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T13%3A18%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Peach%20allergy%20in%20spanish%20children:%20tolerance%20to%20the%20pulp%20and%20molecular%20sensitization%20profile&rft.jtitle=Pediatric%20allergy%20and%20immunology&rft.au=Boyano-Mart%C3%ADnez,%20Teresa&rft.date=2013-03&rft.volume=24&rft.issue=2&rft.spage=168&rft.epage=172&rft.pages=168-172&rft.issn=0905-6157&rft.eissn=1399-3038&rft_id=info:doi/10.1111/pai.12037&rft_dat=%3Cproquest_cross%3E1323807056%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1434147617&rft_id=info:pmid/23506291&rfr_iscdi=true |