Fetal genetic risk of isolated cleft lip only versus isolated cleft lip and palate: A subphenotype analysis using two population-based studies of orofacial clefts in scandinavia

BACKGROUND: Cleft lip only (CLO) and cleft lip and palate (CLP) are commonly regarded as variants of the same defect and are traditionally combined to form the single group of cleft lip with or without cleft palate (CL/P) prior to analysis. However, recent data have suggested that at least a subgrou...

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Veröffentlicht in:	Birth defects research. A Clinical and molecular teratology 2011-02, Vol.91 (2), p.85-92
Hauptverfasser:	Jugessur, Astanand, Shi, Min, Gjessing, Håkon Kristian, Lie, Rolv Terje, Wilcox, Allen James, Weinberg, Clarice Ring, Christensen, Kaare, Boyles, Abee Lowman, Daack-Hirsch, Sandra, Nguyen, Truc Trung, Christiansen, Lene, Lidral, Andrew Carl, Murray, Jeffrey Clark
Format:	Artikel
Sprache:	eng
Schlagworte:	birth defects cleft lip Cleft Lip - epidemiology Cleft Lip - genetics Cleft lip/palate cleft palate Cleft Palate - epidemiology Cleft Palate - genetics Congenital defects Connexin 43 Connexin 43 - genetics Data processing Female Fetuses Fibroblast Growth Factors - genetics Genetic Association Studies genetic epidemiology Genetic Predisposition to Disease Genotypes Humans Interferon Regulatory Factors - genetics Male orofacial cleft orofacial clefts Phenotype Polymorphism, Single Nucleotide Population studies Scandinavian and Nordic Countries - epidemiology Single-nucleotide polymorphism Statistics Vinculin - genetics
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