Genome-wide CpG island methylation analyses in non-small cell lung cancer patients

DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathogenesis of cancer. We performed a genome-wide search for methylated CpG islands in tumors and corresponding non-malignant lung tissue samples of 101 stages I-III non-small cell lung cancer (NSCLC) patie...

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Veröffentlicht in:	Carcinogenesis (New York) 2013-03, Vol.34 (3), p.513-521
Hauptverfasser:	Heller, Gerwin, Babinsky, Valerie N, Ziegler, Barbara, Weinzierl, Marlene, Noll, Christian, Altenberger, Corinna, Müllauer, Leonhard, Dekan, Gerhard, Grin, Yuliya, Lang, György, End-Pfützenreuter, Adelheid, Steiner, Irene, Zehetmayer, Sonja, Döme, Balazs, Arns, Britt-Madeleine, Fong, Kwun M, Wright, Casey M, Yang, Ian A, Klepetko, Walter, Posch, Martin, Zielinski, Christoph C, Zöchbauer-Müller, Sabine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - mortality Base Sequence Cadherins - genetics Cadherins - metabolism Carcinogenesis Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - mortality Chromosome Mapping CpG Islands DNA Methylation Female Gene Expression Regulation, Neoplastic Genes, Neoplasm Genome-Wide Association Study Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humans Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - mortality Male Middle Aged Oligonucleotide Array Sequence Analysis ROC Curve Sequence Analysis, DNA Transcriptome
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