Accuracy of Determining Hemoglobin Level Using Occlusion Spectroscopy in Patients with Severe Gastrointestinal Bleeding
In patients presenting with severe hemorrhage, the authors conducted an equivalence trial that compared noninvasive occlusion spectroscopy and the capillary blood method to determine hemoglobin level. This prospective observational study included patients admitted to their intensive care unit for ga...
Gespeichert in:
| Veröffentlicht in: | Anesthesiology (Philadelphia) 2013-03, Vol.118 (3), p.640-648 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 648 |
|---|---|
| container_issue | 3 |
| container_start_page | 640 |
| container_title | Anesthesiology (Philadelphia) |
| container_volume | 118 |
| creator | COQUIN, Julien BERTARREX, Amandine DEWITTE, Antoine LEFEVRE, Laurent JOANNES-BOYAU, Olivier FLEUREAU, Catherine WINNOCK, Stéphane LEUILLET, Sébastien JANVIER, Gerard OUATTARA, Alexandre |
| description | In patients presenting with severe hemorrhage, the authors conducted an equivalence trial that compared noninvasive occlusion spectroscopy and the capillary blood method to determine hemoglobin level.
This prospective observational study included patients admitted to their intensive care unit for gastrointestinal bleeding. A ring-shaped sensor, connected to a NBM-200MP (OrSense, Nes Ziona, Israel), was fitted onto the patient's thumb to intermittently measure hemoglobin (SotHb). During the first 24 h after admission, venous hemoglobin level, considered as the reference method, was determined at the laboratory every 8 h and was compared to SotHb and the capillary blood method. The primary endpoint was the proportion of inaccurate measurements, defined as greater than 15% difference compared with reference values or their unavailability for any technical reason.
The study was scheduled to include 68 patients but was stopped prematurely after an interim analysis of 34 patients. The proportion of inaccuracies revealed that SotHb could not be considered equivalent to the capillary blood method (47% [95% CI, 43-51] and 24% [95% CI, 20-28]). Considering venous hemoglobin level as a reference method, the mean biases for SotHb (n = 133) and the capillary blood method (n = 135) were, respectively, -0.4 ± 2.0 and 0.8 ± 1.2 g/dl (P < 0.05). SotHb was associated with an increased incidence of failed transfusion. The inaccuracy of SotHb tended to be increased in patients receiving vasopressor agents.
Noninvasive determination of hemoglobin level based on occlusion spectroscopy lacks accuracy in patients presenting with severe gastrointestinal bleeding and cannot be considered equivalent to the capillary-based method. This inaccuracy seems to be moderately influenced by the infusion of vasopressor agents. |
| doi_str_mv | 10.1097/ALN.0b013e3182833fcc |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1323797533</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1323797533</sourcerecordid><originalsourceid>FETCH-LOGICAL-c383t-807a9a6fd8f10453b774a21a574123bf103e673913220edd17bdb6d2590c000e3</originalsourceid><addsrcrecordid>eNpdkFFP2zAQx61paHSwbzAhv0zaS4rPl9TJYwejnVQBEuM5cpxLZ-Q4xU6G-u0xomMSTyeffv8734-xryDmICp1vtxcz0UjAAmhlCViZ8wHNoNClhmAKj6ymRACMxRSHrPPMT6kpyqw_MSOJSLksChn7GlpzBS02fOh45c0Uuitt37L19QPWzc01vMN_SXH7-NL-8YYN0U7eH63IzOGIZpht-eJutWjJT9G_mTHP_wuZQLxlY6JsX6kOFqvHf_hiNo06JQdddpF-nKoJ-z-6ufvi3W2uVn9ulhuMoMljlkplK70omvLDkReYKNUriXoQuUgsUlNpIXCClBKQW0LqmmbRSuLSph0LuEJ-_46dxeGxyn9ou5tNOSc9jRMsU5BVFXSggnNX1GTroqBunoXbK_DvgZRvyivk_L6vfIUOztsmJqe2rfQP8cJ-HYAdDTadUF7Y-N_ToEoQAl8Bg4Di84</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1323797533</pqid></control><display><type>article</type><title>Accuracy of Determining Hemoglobin Level Using Occlusion Spectroscopy in Patients with Severe Gastrointestinal Bleeding</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>COQUIN, Julien ; BERTARREX, Amandine ; DEWITTE, Antoine ; LEFEVRE, Laurent ; JOANNES-BOYAU, Olivier ; FLEUREAU, Catherine ; WINNOCK, Stéphane ; LEUILLET, Sébastien ; JANVIER, Gerard ; OUATTARA, Alexandre</creator><creatorcontrib>COQUIN, Julien ; BERTARREX, Amandine ; DEWITTE, Antoine ; LEFEVRE, Laurent ; JOANNES-BOYAU, Olivier ; FLEUREAU, Catherine ; WINNOCK, Stéphane ; LEUILLET, Sébastien ; JANVIER, Gerard ; OUATTARA, Alexandre</creatorcontrib><description>In patients presenting with severe hemorrhage, the authors conducted an equivalence trial that compared noninvasive occlusion spectroscopy and the capillary blood method to determine hemoglobin level.
This prospective observational study included patients admitted to their intensive care unit for gastrointestinal bleeding. A ring-shaped sensor, connected to a NBM-200MP (OrSense, Nes Ziona, Israel), was fitted onto the patient's thumb to intermittently measure hemoglobin (SotHb). During the first 24 h after admission, venous hemoglobin level, considered as the reference method, was determined at the laboratory every 8 h and was compared to SotHb and the capillary blood method. The primary endpoint was the proportion of inaccurate measurements, defined as greater than 15% difference compared with reference values or their unavailability for any technical reason.
The study was scheduled to include 68 patients but was stopped prematurely after an interim analysis of 34 patients. The proportion of inaccuracies revealed that SotHb could not be considered equivalent to the capillary blood method (47% [95% CI, 43-51] and 24% [95% CI, 20-28]). Considering venous hemoglobin level as a reference method, the mean biases for SotHb (n = 133) and the capillary blood method (n = 135) were, respectively, -0.4 ± 2.0 and 0.8 ± 1.2 g/dl (P < 0.05). SotHb was associated with an increased incidence of failed transfusion. The inaccuracy of SotHb tended to be increased in patients receiving vasopressor agents.
Noninvasive determination of hemoglobin level based on occlusion spectroscopy lacks accuracy in patients presenting with severe gastrointestinal bleeding and cannot be considered equivalent to the capillary-based method. This inaccuracy seems to be moderately influenced by the infusion of vasopressor agents.</description><identifier>ISSN: 0003-3022</identifier><identifier>EISSN: 1528-1175</identifier><identifier>DOI: 10.1097/ALN.0b013e3182833fcc</identifier><identifier>PMID: 23314168</identifier><identifier>CODEN: ANESAV</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Aged ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Female ; Gastrointestinal Hemorrhage - blood ; Gastrointestinal Hemorrhage - diagnosis ; Gastrointestinal Hemorrhage - therapy ; Hemoglobinometry - instrumentation ; Hemoglobinometry - methods ; Hemoglobinometry - standards ; Hemoglobins - metabolism ; Hemoglobins - standards ; Humans ; Male ; Medical sciences ; Middle Aged ; Oximetry - instrumentation ; Oximetry - methods ; Oximetry - standards ; Prospective Studies ; Secondary Prevention ; Severity of Illness Index ; Spectrum Analysis - instrumentation ; Spectrum Analysis - methods ; Spectrum Analysis - standards</subject><ispartof>Anesthesiology (Philadelphia), 2013-03, Vol.118 (3), p.640-648</ispartof><rights>2014 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c383t-807a9a6fd8f10453b774a21a574123bf103e673913220edd17bdb6d2590c000e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27105170$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23314168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>COQUIN, Julien</creatorcontrib><creatorcontrib>BERTARREX, Amandine</creatorcontrib><creatorcontrib>DEWITTE, Antoine</creatorcontrib><creatorcontrib>LEFEVRE, Laurent</creatorcontrib><creatorcontrib>JOANNES-BOYAU, Olivier</creatorcontrib><creatorcontrib>FLEUREAU, Catherine</creatorcontrib><creatorcontrib>WINNOCK, Stéphane</creatorcontrib><creatorcontrib>LEUILLET, Sébastien</creatorcontrib><creatorcontrib>JANVIER, Gerard</creatorcontrib><creatorcontrib>OUATTARA, Alexandre</creatorcontrib><title>Accuracy of Determining Hemoglobin Level Using Occlusion Spectroscopy in Patients with Severe Gastrointestinal Bleeding</title><title>Anesthesiology (Philadelphia)</title><addtitle>Anesthesiology</addtitle><description>In patients presenting with severe hemorrhage, the authors conducted an equivalence trial that compared noninvasive occlusion spectroscopy and the capillary blood method to determine hemoglobin level.
This prospective observational study included patients admitted to their intensive care unit for gastrointestinal bleeding. A ring-shaped sensor, connected to a NBM-200MP (OrSense, Nes Ziona, Israel), was fitted onto the patient's thumb to intermittently measure hemoglobin (SotHb). During the first 24 h after admission, venous hemoglobin level, considered as the reference method, was determined at the laboratory every 8 h and was compared to SotHb and the capillary blood method. The primary endpoint was the proportion of inaccurate measurements, defined as greater than 15% difference compared with reference values or their unavailability for any technical reason.
The study was scheduled to include 68 patients but was stopped prematurely after an interim analysis of 34 patients. The proportion of inaccuracies revealed that SotHb could not be considered equivalent to the capillary blood method (47% [95% CI, 43-51] and 24% [95% CI, 20-28]). Considering venous hemoglobin level as a reference method, the mean biases for SotHb (n = 133) and the capillary blood method (n = 135) were, respectively, -0.4 ± 2.0 and 0.8 ± 1.2 g/dl (P < 0.05). SotHb was associated with an increased incidence of failed transfusion. The inaccuracy of SotHb tended to be increased in patients receiving vasopressor agents.
Noninvasive determination of hemoglobin level based on occlusion spectroscopy lacks accuracy in patients presenting with severe gastrointestinal bleeding and cannot be considered equivalent to the capillary-based method. This inaccuracy seems to be moderately influenced by the infusion of vasopressor agents.</description><subject>Aged</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Gastrointestinal Hemorrhage - blood</subject><subject>Gastrointestinal Hemorrhage - diagnosis</subject><subject>Gastrointestinal Hemorrhage - therapy</subject><subject>Hemoglobinometry - instrumentation</subject><subject>Hemoglobinometry - methods</subject><subject>Hemoglobinometry - standards</subject><subject>Hemoglobins - metabolism</subject><subject>Hemoglobins - standards</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Oximetry - instrumentation</subject><subject>Oximetry - methods</subject><subject>Oximetry - standards</subject><subject>Prospective Studies</subject><subject>Secondary Prevention</subject><subject>Severity of Illness Index</subject><subject>Spectrum Analysis - instrumentation</subject><subject>Spectrum Analysis - methods</subject><subject>Spectrum Analysis - standards</subject><issn>0003-3022</issn><issn>1528-1175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkFFP2zAQx61paHSwbzAhv0zaS4rPl9TJYwejnVQBEuM5cpxLZ-Q4xU6G-u0xomMSTyeffv8734-xryDmICp1vtxcz0UjAAmhlCViZ8wHNoNClhmAKj6ymRACMxRSHrPPMT6kpyqw_MSOJSLksChn7GlpzBS02fOh45c0Uuitt37L19QPWzc01vMN_SXH7-NL-8YYN0U7eH63IzOGIZpht-eJutWjJT9G_mTHP_wuZQLxlY6JsX6kOFqvHf_hiNo06JQdddpF-nKoJ-z-6ufvi3W2uVn9ulhuMoMljlkplK70omvLDkReYKNUriXoQuUgsUlNpIXCClBKQW0LqmmbRSuLSph0LuEJ-_46dxeGxyn9ou5tNOSc9jRMsU5BVFXSggnNX1GTroqBunoXbK_DvgZRvyivk_L6vfIUOztsmJqe2rfQP8cJ-HYAdDTadUF7Y-N_ToEoQAl8Bg4Di84</recordid><startdate>20130301</startdate><enddate>20130301</enddate><creator>COQUIN, Julien</creator><creator>BERTARREX, Amandine</creator><creator>DEWITTE, Antoine</creator><creator>LEFEVRE, Laurent</creator><creator>JOANNES-BOYAU, Olivier</creator><creator>FLEUREAU, Catherine</creator><creator>WINNOCK, Stéphane</creator><creator>LEUILLET, Sébastien</creator><creator>JANVIER, Gerard</creator><creator>OUATTARA, Alexandre</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130301</creationdate><title>Accuracy of Determining Hemoglobin Level Using Occlusion Spectroscopy in Patients with Severe Gastrointestinal Bleeding</title><author>COQUIN, Julien ; BERTARREX, Amandine ; DEWITTE, Antoine ; LEFEVRE, Laurent ; JOANNES-BOYAU, Olivier ; FLEUREAU, Catherine ; WINNOCK, Stéphane ; LEUILLET, Sébastien ; JANVIER, Gerard ; OUATTARA, Alexandre</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c383t-807a9a6fd8f10453b774a21a574123bf103e673913220edd17bdb6d2590c000e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Gastrointestinal Hemorrhage - blood</topic><topic>Gastrointestinal Hemorrhage - diagnosis</topic><topic>Gastrointestinal Hemorrhage - therapy</topic><topic>Hemoglobinometry - instrumentation</topic><topic>Hemoglobinometry - methods</topic><topic>Hemoglobinometry - standards</topic><topic>Hemoglobins - metabolism</topic><topic>Hemoglobins - standards</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Oximetry - instrumentation</topic><topic>Oximetry - methods</topic><topic>Oximetry - standards</topic><topic>Prospective Studies</topic><topic>Secondary Prevention</topic><topic>Severity of Illness Index</topic><topic>Spectrum Analysis - instrumentation</topic><topic>Spectrum Analysis - methods</topic><topic>Spectrum Analysis - standards</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>COQUIN, Julien</creatorcontrib><creatorcontrib>BERTARREX, Amandine</creatorcontrib><creatorcontrib>DEWITTE, Antoine</creatorcontrib><creatorcontrib>LEFEVRE, Laurent</creatorcontrib><creatorcontrib>JOANNES-BOYAU, Olivier</creatorcontrib><creatorcontrib>FLEUREAU, Catherine</creatorcontrib><creatorcontrib>WINNOCK, Stéphane</creatorcontrib><creatorcontrib>LEUILLET, Sébastien</creatorcontrib><creatorcontrib>JANVIER, Gerard</creatorcontrib><creatorcontrib>OUATTARA, Alexandre</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesiology (Philadelphia)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>COQUIN, Julien</au><au>BERTARREX, Amandine</au><au>DEWITTE, Antoine</au><au>LEFEVRE, Laurent</au><au>JOANNES-BOYAU, Olivier</au><au>FLEUREAU, Catherine</au><au>WINNOCK, Stéphane</au><au>LEUILLET, Sébastien</au><au>JANVIER, Gerard</au><au>OUATTARA, Alexandre</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Accuracy of Determining Hemoglobin Level Using Occlusion Spectroscopy in Patients with Severe Gastrointestinal Bleeding</atitle><jtitle>Anesthesiology (Philadelphia)</jtitle><addtitle>Anesthesiology</addtitle><date>2013-03-01</date><risdate>2013</risdate><volume>118</volume><issue>3</issue><spage>640</spage><epage>648</epage><pages>640-648</pages><issn>0003-3022</issn><eissn>1528-1175</eissn><coden>ANESAV</coden><abstract>In patients presenting with severe hemorrhage, the authors conducted an equivalence trial that compared noninvasive occlusion spectroscopy and the capillary blood method to determine hemoglobin level.
This prospective observational study included patients admitted to their intensive care unit for gastrointestinal bleeding. A ring-shaped sensor, connected to a NBM-200MP (OrSense, Nes Ziona, Israel), was fitted onto the patient's thumb to intermittently measure hemoglobin (SotHb). During the first 24 h after admission, venous hemoglobin level, considered as the reference method, was determined at the laboratory every 8 h and was compared to SotHb and the capillary blood method. The primary endpoint was the proportion of inaccurate measurements, defined as greater than 15% difference compared with reference values or their unavailability for any technical reason.
The study was scheduled to include 68 patients but was stopped prematurely after an interim analysis of 34 patients. The proportion of inaccuracies revealed that SotHb could not be considered equivalent to the capillary blood method (47% [95% CI, 43-51] and 24% [95% CI, 20-28]). Considering venous hemoglobin level as a reference method, the mean biases for SotHb (n = 133) and the capillary blood method (n = 135) were, respectively, -0.4 ± 2.0 and 0.8 ± 1.2 g/dl (P < 0.05). SotHb was associated with an increased incidence of failed transfusion. The inaccuracy of SotHb tended to be increased in patients receiving vasopressor agents.
Noninvasive determination of hemoglobin level based on occlusion spectroscopy lacks accuracy in patients presenting with severe gastrointestinal bleeding and cannot be considered equivalent to the capillary-based method. This inaccuracy seems to be moderately influenced by the infusion of vasopressor agents.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>23314168</pmid><doi>10.1097/ALN.0b013e3182833fcc</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-3022 |
| ispartof | Anesthesiology (Philadelphia), 2013-03, Vol.118 (3), p.640-648 |
| issn | 0003-3022 1528-1175 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1323797533 |
| source | MEDLINE; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Female Gastrointestinal Hemorrhage - blood Gastrointestinal Hemorrhage - diagnosis Gastrointestinal Hemorrhage - therapy Hemoglobinometry - instrumentation Hemoglobinometry - methods Hemoglobinometry - standards Hemoglobins - metabolism Hemoglobins - standards Humans Male Medical sciences Middle Aged Oximetry - instrumentation Oximetry - methods Oximetry - standards Prospective Studies Secondary Prevention Severity of Illness Index Spectrum Analysis - instrumentation Spectrum Analysis - methods Spectrum Analysis - standards |
| title | Accuracy of Determining Hemoglobin Level Using Occlusion Spectroscopy in Patients with Severe Gastrointestinal Bleeding |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T07%3A28%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Accuracy%20of%20Determining%20Hemoglobin%20Level%20Using%20Occlusion%20Spectroscopy%20in%20Patients%20with%20Severe%20Gastrointestinal%20Bleeding&rft.jtitle=Anesthesiology%20(Philadelphia)&rft.au=COQUIN,%20Julien&rft.date=2013-03-01&rft.volume=118&rft.issue=3&rft.spage=640&rft.epage=648&rft.pages=640-648&rft.issn=0003-3022&rft.eissn=1528-1175&rft.coden=ANESAV&rft_id=info:doi/10.1097/ALN.0b013e3182833fcc&rft_dat=%3Cproquest_cross%3E1323797533%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1323797533&rft_id=info:pmid/23314168&rfr_iscdi=true |