Hydrocortisone inhibits IFN-γ production in equine, ovine, and bovine PBMCs

Hydrocortisone is widely accepted as an anti-inflammatory agent and there are many products available containing hydrocortisone as an active ingredient. Surprisingly, there is little data available specifically on the immunological effects of hydrocortisone in large animals. Glucocorticoids are well...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2013-05, Vol.153 (1-2), p.128-133
Hauptverfasser:	McCandless, Erin E., Rai, Sharath K., Mwangi, Duncan, Sly, Laurel, Franz, Lilian C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Bovine Cattle Dose-Response Relationship, Drug Equine Flow Cytometry Horses Hydrocortisone Hydrocortisone - pharmacology IFN-γ Interferon-gamma - biosynthesis Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology Ovine Sheep Species Specificity T-Lymphocytes - drug effects T-Lymphocytes - immunology
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