Acute atorvastatin treatment exerts antidepressant-like effect in mice via the l -arginine–nitric oxide–cyclic guanosine monophosphate pathway and increases BDNF levels

Abstract Atorvastatin is a synthetic and lipophilic statin that presents a good effect in decreasing cholesterol levels and is safe and well tolerated. Population-based studies have suggested a positive role of statins in reducing depression risk. This study aimed at investigating the atorvastatin e...

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