A Rare Case of Propofol-induced Liver Injury during Modified Electroconvulsive Therapy in an Elderly Woman
A 75-year-old woman developed depression in 2010 and was treated with oral medications at our Department of Psychiatry. Since she showed no tendency toward improvement, she underwent modified electroconvulsive therapy (mECT). Later, she developed severe liver injury that was presumably induced by th...
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| Veröffentlicht in: | Internal Medicine 2013, Vol.52(7), pp.761-765 |
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| container_title | Internal Medicine |
| container_volume | 52 |
| creator | Asai, Akira Yagi, Mai Tsuchimoto, Yusuke Fukunishi, Shinya Takeshita, Atsushi Tsuda, Yasuhiro Fukuda, Akira Higuchi, Kazuhide |
| description | A 75-year-old woman developed depression in 2010 and was treated with oral medications at our Department of Psychiatry. Since she showed no tendency toward improvement, she underwent modified electroconvulsive therapy (mECT). Later, she developed severe liver injury that was presumably induced by the propofol used for mECT. Propofol is an intravenous anesthetic agent that reportedly can be used relatively safely in the presence of liver dysfunction. We herein report the first case of propofol-induced liver injury definitively diagnosed based on positive drug lympocyte stimulation testing (DLST). |
| doi_str_mv | 10.2169/internalmedicine.52.9089 |
| format | Article |
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Since she showed no tendency toward improvement, she underwent modified electroconvulsive therapy (mECT). Later, she developed severe liver injury that was presumably induced by the propofol used for mECT. Propofol is an intravenous anesthetic agent that reportedly can be used relatively safely in the presence of liver dysfunction. 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We herein report the first case of propofol-induced liver injury definitively diagnosed based on positive drug lympocyte stimulation testing (DLST).</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>23545671</pmid><doi>10.2169/internalmedicine.52.9089</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Internal Medicine, 2013, Vol.52(7), pp.761-765 |
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| language | eng |
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| source | J-STAGE Free; MEDLINE |
| subjects | Aged Chemical and Drug Induced Liver Injury - blood Chemical and Drug Induced Liver Injury - diagnosis Electroconvulsive Therapy - adverse effects Female Humans liver injury modified electroconvulsive therapy propofol Propofol - adverse effects |
| title | A Rare Case of Propofol-induced Liver Injury during Modified Electroconvulsive Therapy in an Elderly Woman |
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