High-sensitivity anastigmatic imaging needle for optical coherence tomography
We present a high-optical-quality imaging needle for optical coherence tomography (OCT) that achieves sensitivity and resolution comparable to conventional free-space OCT sample arms. The side-viewing needle design utilizes total internal reflection from an angle-polished fiber tip, encased in a gla...
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Veröffentlicht in: | Optics letters 2012-12, Vol.37 (24), p.5247-5249 |
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creator | Scolaro, Loretta Lorenser, Dirk McLaughlin, Robert A Quirk, Bryden C Kirk, Rodney W Sampson, David D |
description | We present a high-optical-quality imaging needle for optical coherence tomography (OCT) that achieves sensitivity and resolution comparable to conventional free-space OCT sample arms. The side-viewing needle design utilizes total internal reflection from an angle-polished fiber tip, encased in a glass microcapillary. Fusion of the capillary to the fiber provides a robust, optical-quality output window. The needle's focusing optics are based on an astigmatism-free design, which exploits the "focal shift" phenomenon for focused Gaussian beams to achieve equal working distances (WDs) for both axes. We present a fabricated needle with a WD ratio of 0.98 for imaging in an aqueous environment. Our needle achieves the highest sensitivity of currently reported OCT imaging needles (112 dB), and we demonstrate its performance by superficial imaging of human skin and 3D volumetric imaging within a biological sample. |
doi_str_mv | 10.1364/OL.37.005247 |
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Our needle achieves the highest sensitivity of currently reported OCT imaging needles (112 dB), and we demonstrate its performance by superficial imaging of human skin and 3D volumetric imaging within a biological sample.</description><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Focusing</subject><subject>Gaussian beams (optics)</subject><subject>Image Enhancement - instrumentation</subject><subject>Imaging</subject><subject>Lenses</subject><subject>Needles</subject><subject>Noise levels</subject><subject>Optical Coherence Tomography</subject><subject>Optical fibers</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Three dimensional</subject><subject>Tomography, Optical Coherence - instrumentation</subject><issn>0146-9592</issn><issn>1539-4794</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1PwzAURS0EoqWwMaOMDKT4M45HVAFFCuoCs-XYTmqUxMFOkfrvMWphZXp6eudd6R4ArhFcIlLQ-021JHwJIcOUn4A5YkTklAt6CuYQ0SIXTOAZuIjxA0JYcELOwQwTzMq0zMHr2rXbPNohusl9uWmfqUHFybW9mpzOXK9aN7TZYK3pbNb4kPkxHVSXab-1wQ7aZpPvfRvUuN1fgrNGddFeHecCvD89vq3WebV5flk9VLkmBZ9yCo0ypqaC4YJAIxgiCHHOsKE1K7VB3DRQcZ1KGYGxaqBIRPpirLaNgGQBbg-5Y_CfOxsn2buobdepwfpdlIikhrgUtPwfxZxQSAUUCb07oDr4GINt5BiSgLCXCMof13JTScLlwXXCb47Ju7q35g_-lUu-ASW9eNw</recordid><startdate>20121215</startdate><enddate>20121215</enddate><creator>Scolaro, Loretta</creator><creator>Lorenser, Dirk</creator><creator>McLaughlin, Robert A</creator><creator>Quirk, Bryden C</creator><creator>Kirk, Rodney W</creator><creator>Sampson, David D</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20121215</creationdate><title>High-sensitivity anastigmatic imaging needle for optical coherence tomography</title><author>Scolaro, Loretta ; Lorenser, Dirk ; McLaughlin, Robert A ; Quirk, Bryden C ; Kirk, Rodney W ; Sampson, David D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-40daddb4952630d9513117752d4b58cd17df0a7c005d922af0913140d55bef903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Focusing</topic><topic>Gaussian beams (optics)</topic><topic>Image Enhancement - instrumentation</topic><topic>Imaging</topic><topic>Lenses</topic><topic>Needles</topic><topic>Noise levels</topic><topic>Optical Coherence Tomography</topic><topic>Optical fibers</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Three dimensional</topic><topic>Tomography, Optical Coherence - instrumentation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scolaro, Loretta</creatorcontrib><creatorcontrib>Lorenser, Dirk</creatorcontrib><creatorcontrib>McLaughlin, Robert A</creatorcontrib><creatorcontrib>Quirk, Bryden C</creatorcontrib><creatorcontrib>Kirk, Rodney W</creatorcontrib><creatorcontrib>Sampson, David D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Optics letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scolaro, Loretta</au><au>Lorenser, Dirk</au><au>McLaughlin, Robert A</au><au>Quirk, Bryden C</au><au>Kirk, Rodney W</au><au>Sampson, David D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High-sensitivity anastigmatic imaging needle for optical coherence tomography</atitle><jtitle>Optics letters</jtitle><addtitle>Opt Lett</addtitle><date>2012-12-15</date><risdate>2012</risdate><volume>37</volume><issue>24</issue><spage>5247</spage><epage>5249</epage><pages>5247-5249</pages><issn>0146-9592</issn><eissn>1539-4794</eissn><abstract>We present a high-optical-quality imaging needle for optical coherence tomography (OCT) that achieves sensitivity and resolution comparable to conventional free-space OCT sample arms. 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source | MEDLINE; Optica Publishing Group Journals |
subjects | Equipment Design Equipment Failure Analysis Focusing Gaussian beams (optics) Image Enhancement - instrumentation Imaging Lenses Needles Noise levels Optical Coherence Tomography Optical fibers Reproducibility of Results Sensitivity and Specificity Three dimensional Tomography, Optical Coherence - instrumentation |
title | High-sensitivity anastigmatic imaging needle for optical coherence tomography |
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