Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity

The enteric nervous system contains excitatory and inhibitory neurons, which control contraction and relaxation of smooth muscle cells as well as gastrointestinal motor activity. Little is known about the exact cellular mechanisms of neuronal signal transduction to smooth muscle cells in the gut. He...

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Veröffentlicht in:	Nature communications 2013, Vol.4 (1), p.1630-1630, Article 1630
Hauptverfasser:	Klein, Sabine, Seidler, Barbara, Kettenberger, Anna, Sibaev, Andrei, Rohn, Michael, Feil, Robert, Allescher, Hans-Dieter, Vanderwinden, Jean-Marie, Hofmann, Franz, Schemann, Michael, Rad, Roland, Storr, Martin A., Schmid, Roland M., Schneider, Günter, Saur, Dieter
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1959/1315/1951 631/378/548 692/699/1503 Animals Cells, Cultured Colon Cyclic GMP-Dependent Protein Kinase Type I - genetics Enteric Nervous System - physiology Genetic engineering Humanities and Social Sciences Internal medicine Interstitial Cells of Cajal - physiology Kinases Large intestine Mice Mice, Transgenic Motility multidisciplinary Nervous system Pacemakers Proteins Science Science (multidisciplinary) Signal transduction Small intestine Smooth muscle Synaptic Transmission
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