In Vitro Fertilization Alters Growth and Expression of Igf2/H19 and Their Epigenetic Mechanisms in the Liver and Skeletal Muscle of Newborn and Elder Mice

Epidemiological studies have reported a higher incidence of growth disorders among newborns conceived by in vitro fertilization (IVF), suggesting that IVF may be disruptive to the process of embryonic and fetal growth. However, the long-term effects of IVF on the growth and molecular mechanisms rema...

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Veröffentlicht in:	Biology of reproduction 2013-03, Vol.88 (3), p.75-75
Hauptverfasser:	Le, Fang, Wang, Li Ya, Wang, Ning, Li, Lei, Li, Le Jun, Zheng, Ying Ming, Lou, Hang Ying, Liu, Xiao Zhen, Xu, Xiang Rong, Sheng, Jian Zhong, Huang, He Feng, Jin, Fan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences Body Weight DNA Methylation Epigenesis, Genetic Female Fertilization in Vitro - adverse effects Fundamental and applied biological sciences. Psychology Insulin-Like Growth Factor II - metabolism Liver - growth & development Male Mice Mice, Inbred C57BL MicroRNAs - metabolism Models, Animal Muscle, Skeletal - growth & development Organ Size Pregnancy Pregnancy Outcome Receptor, IGF Type 2 - metabolism RNA, Long Noncoding - metabolism Striated muscle. Tendons Vertebrates: osteoarticular system, musculoskeletal system Vertebrates: reproduction
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