In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations
The purpose of this study is to evaluate and compare the clinical and radiographic effectiveness of Ciprofloxacin, Minocycline, Metronidazole combination with Ciprofloxacin, Minocycline and Tinidazole combination when used for Lesion Sterilization and Tissue Repair in primary teeth. 25 healthy child...
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Veröffentlicht in: | The Journal of clinical pediatric dentistry 2012-12, Vol.37 (2), p.189-191 |
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creator | Jaya, A R Praveen, P Anantharaj, A Venkataraghavan, Karthik Rani, Prathibha S |
description | The purpose of this study is to evaluate and compare the clinical and radiographic effectiveness of Ciprofloxacin, Minocycline, Metronidazole combination with Ciprofloxacin, Minocycline and Tinidazole combination when used for Lesion Sterilization and Tissue Repair in primary teeth.
25 healthy children, visiting Dept. of Pediatric & Preventive Dentistry, D.A.P.M.R.V. Dental College, Bangalore, India, aged between 6-9 years who were having 30 infected primary teeth are selected and divided into 2 groups. In Group A, a mixture of 3mix-MP Ciprofloxacin, Metronidazole and Minocycline was placed on the floor of the pulp chamber covering the root canal orifices. In Group B a mixture of Ciprofloxacin, Tinidazole and Minocycline was placed as a layer on the floor of the pulp chamber. The procedure was completed in a single visit. Post operative clinical evaluation was done after 1,6,12 and 24 months. Postoperative radiographic evaluation was done at 6, 12 and 24 months.
No statistically significant difference is observed between both the groups and a combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs can be used on teeth pulpally involved with physiologic root resorption.
After a 24 Month follow up, we can conclude that primary teeth with the periradicular lesions, can be conserved by using combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs. |
doi_str_mv | 10.17796/jcpd.37.2.e5131jp6m1w33v66 |
format | Article |
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25 healthy children, visiting Dept. of Pediatric & Preventive Dentistry, D.A.P.M.R.V. Dental College, Bangalore, India, aged between 6-9 years who were having 30 infected primary teeth are selected and divided into 2 groups. In Group A, a mixture of 3mix-MP Ciprofloxacin, Metronidazole and Minocycline was placed on the floor of the pulp chamber covering the root canal orifices. In Group B a mixture of Ciprofloxacin, Tinidazole and Minocycline was placed as a layer on the floor of the pulp chamber. The procedure was completed in a single visit. Post operative clinical evaluation was done after 1,6,12 and 24 months. Postoperative radiographic evaluation was done at 6, 12 and 24 months.
No statistically significant difference is observed between both the groups and a combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs can be used on teeth pulpally involved with physiologic root resorption.
After a 24 Month follow up, we can conclude that primary teeth with the periradicular lesions, can be conserved by using combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs.</description><identifier>ISSN: 1053-4628</identifier><identifier>EISSN: 1557-5268</identifier><identifier>DOI: 10.17796/jcpd.37.2.e5131jp6m1w33v66</identifier><identifier>PMID: 23534328</identifier><language>eng</language><publisher>United States</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Child ; Ciprofloxacin - therapeutic use ; Dental Pulp Necrosis - diagnostic imaging ; Dental Pulp Necrosis - drug therapy ; Dentistry ; Double-Blind Method ; Drug Combinations ; Humans ; Metronidazole - therapeutic use ; Minocycline - therapeutic use ; Pain, Postoperative - prevention & control ; Periapical Abscess - prevention & control ; Radiography ; Regeneration ; Root Canal Irrigants - therapeutic use ; Root Resorption ; Tinidazole - therapeutic use ; Tooth Mobility - prevention & control ; Tooth, Deciduous ; Treatment Outcome</subject><ispartof>The Journal of clinical pediatric dentistry, 2012-12, Vol.37 (2), p.189-191</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c321t-d213295db365b602dd3aef744cacd72526672c45189698af23ab45af9084e8e23</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23534328$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jaya, A R</creatorcontrib><creatorcontrib>Praveen, P</creatorcontrib><creatorcontrib>Anantharaj, A</creatorcontrib><creatorcontrib>Venkataraghavan, Karthik</creatorcontrib><creatorcontrib>Rani, Prathibha S</creatorcontrib><title>In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations</title><title>The Journal of clinical pediatric dentistry</title><addtitle>J Clin Pediatr Dent</addtitle><description>The purpose of this study is to evaluate and compare the clinical and radiographic effectiveness of Ciprofloxacin, Minocycline, Metronidazole combination with Ciprofloxacin, Minocycline and Tinidazole combination when used for Lesion Sterilization and Tissue Repair in primary teeth.
25 healthy children, visiting Dept. of Pediatric & Preventive Dentistry, D.A.P.M.R.V. Dental College, Bangalore, India, aged between 6-9 years who were having 30 infected primary teeth are selected and divided into 2 groups. In Group A, a mixture of 3mix-MP Ciprofloxacin, Metronidazole and Minocycline was placed on the floor of the pulp chamber covering the root canal orifices. In Group B a mixture of Ciprofloxacin, Tinidazole and Minocycline was placed as a layer on the floor of the pulp chamber. The procedure was completed in a single visit. Post operative clinical evaluation was done after 1,6,12 and 24 months. Postoperative radiographic evaluation was done at 6, 12 and 24 months.
No statistically significant difference is observed between both the groups and a combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs can be used on teeth pulpally involved with physiologic root resorption.
After a 24 Month follow up, we can conclude that primary teeth with the periradicular lesions, can be conserved by using combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Child</subject><subject>Ciprofloxacin - therapeutic use</subject><subject>Dental Pulp Necrosis - diagnostic imaging</subject><subject>Dental Pulp Necrosis - drug therapy</subject><subject>Dentistry</subject><subject>Double-Blind Method</subject><subject>Drug Combinations</subject><subject>Humans</subject><subject>Metronidazole - therapeutic use</subject><subject>Minocycline - therapeutic use</subject><subject>Pain, Postoperative - prevention & control</subject><subject>Periapical Abscess - prevention & control</subject><subject>Radiography</subject><subject>Regeneration</subject><subject>Root Canal Irrigants - therapeutic use</subject><subject>Root Resorption</subject><subject>Tinidazole - therapeutic use</subject><subject>Tooth Mobility - prevention & control</subject><subject>Tooth, Deciduous</subject><subject>Treatment Outcome</subject><issn>1053-4628</issn><issn>1557-5268</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUU1P3DAUtBAVUNq_gCxx4ZLFH_FHxAkhCkhIvbRny7FfwKskDrazaHvrP29gtxw4vdHTzDzNG4TOKVlRpRp5uXaTX3G1YisQlNP1JAf6yvlGygN0QoVQlWBSHy6YCF7Vkulj9DXnNSFES02O0DHjgtec6RP092HEm7CJGDa2n20JccSxwz3kN5QLpNCHP7u9HT0uIecZcILJhoTDiKcUBpu2uACUZzzN_YTLMyQ7bfGcw_iEy2tclCW0IZbgsE_zE3ZxaMP47pq_oS-d7TN8389T9PvH7a-b--rx593DzfVj5TijpfKMctYI33IpWkmY99xCp-raWecVWxJLxVwtqG5ko23HuG1rYbuG6Bo0MH6KLna-U4ovM-RihpAd9L0dIc7ZLPZUNYIRuVCvdlSXYs4JOrNPaSgx7x2Ytw4MV4aZzx0s6rP9obkdwH9o_z-d_wOPBYmB</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Jaya, A R</creator><creator>Praveen, P</creator><creator>Anantharaj, A</creator><creator>Venkataraghavan, Karthik</creator><creator>Rani, Prathibha S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20121201</creationdate><title>In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations</title><author>Jaya, A R ; Praveen, P ; Anantharaj, A ; Venkataraghavan, Karthik ; Rani, Prathibha S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c321t-d213295db365b602dd3aef744cacd72526672c45189698af23ab45af9084e8e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Child</topic><topic>Ciprofloxacin - therapeutic use</topic><topic>Dental Pulp Necrosis - diagnostic imaging</topic><topic>Dental Pulp Necrosis - drug therapy</topic><topic>Dentistry</topic><topic>Double-Blind Method</topic><topic>Drug Combinations</topic><topic>Humans</topic><topic>Metronidazole - therapeutic use</topic><topic>Minocycline - therapeutic use</topic><topic>Pain, Postoperative - prevention & control</topic><topic>Periapical Abscess - prevention & control</topic><topic>Radiography</topic><topic>Regeneration</topic><topic>Root Canal Irrigants - therapeutic use</topic><topic>Root Resorption</topic><topic>Tinidazole - therapeutic use</topic><topic>Tooth Mobility - prevention & control</topic><topic>Tooth, Deciduous</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jaya, A R</creatorcontrib><creatorcontrib>Praveen, P</creatorcontrib><creatorcontrib>Anantharaj, A</creatorcontrib><creatorcontrib>Venkataraghavan, Karthik</creatorcontrib><creatorcontrib>Rani, Prathibha S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of clinical pediatric dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jaya, A R</au><au>Praveen, P</au><au>Anantharaj, A</au><au>Venkataraghavan, Karthik</au><au>Rani, Prathibha S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations</atitle><jtitle>The Journal of clinical pediatric dentistry</jtitle><addtitle>J Clin Pediatr Dent</addtitle><date>2012-12-01</date><risdate>2012</risdate><volume>37</volume><issue>2</issue><spage>189</spage><epage>191</epage><pages>189-191</pages><issn>1053-4628</issn><eissn>1557-5268</eissn><abstract>The purpose of this study is to evaluate and compare the clinical and radiographic effectiveness of Ciprofloxacin, Minocycline, Metronidazole combination with Ciprofloxacin, Minocycline and Tinidazole combination when used for Lesion Sterilization and Tissue Repair in primary teeth.
25 healthy children, visiting Dept. of Pediatric & Preventive Dentistry, D.A.P.M.R.V. Dental College, Bangalore, India, aged between 6-9 years who were having 30 infected primary teeth are selected and divided into 2 groups. In Group A, a mixture of 3mix-MP Ciprofloxacin, Metronidazole and Minocycline was placed on the floor of the pulp chamber covering the root canal orifices. In Group B a mixture of Ciprofloxacin, Tinidazole and Minocycline was placed as a layer on the floor of the pulp chamber. The procedure was completed in a single visit. Post operative clinical evaluation was done after 1,6,12 and 24 months. Postoperative radiographic evaluation was done at 6, 12 and 24 months.
No statistically significant difference is observed between both the groups and a combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs can be used on teeth pulpally involved with physiologic root resorption.
After a 24 Month follow up, we can conclude that primary teeth with the periradicular lesions, can be conserved by using combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs.</abstract><cop>United States</cop><pmid>23534328</pmid><doi>10.17796/jcpd.37.2.e5131jp6m1w33v66</doi><tpages>3</tpages></addata></record> |
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subjects | Anti-Bacterial Agents - therapeutic use Child Ciprofloxacin - therapeutic use Dental Pulp Necrosis - diagnostic imaging Dental Pulp Necrosis - drug therapy Dentistry Double-Blind Method Drug Combinations Humans Metronidazole - therapeutic use Minocycline - therapeutic use Pain, Postoperative - prevention & control Periapical Abscess - prevention & control Radiography Regeneration Root Canal Irrigants - therapeutic use Root Resorption Tinidazole - therapeutic use Tooth Mobility - prevention & control Tooth, Deciduous Treatment Outcome |
title | In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations |
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