Isogenic human mammary epithelial cell lines: novel tools for target identification and validation: Comprehensive characterization of an isogenic human mammary epithelial cell model provides evidence for epithelial–mesenchymal transition

Tumorigenesis is a multi-step process involving several consecutive genetic alterations resulting in loss of genomic stability and deregulated signal transduction pathways. To study these deregulated processes in vitro, typically established cancer cell lines derived from primary tumors, ascites, or...

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