Ulcers caused by bullous morphea: successful therapy with N-acetylcysteine and topical wound care

Ulcers caused by bullous morphea: successful therapy with N-acetylcysteine and topical wound care

Bullous morphea is an uncommon form of localized scleroderma. The pathogenesis is unknown and treatment of coexistent ulcers is difficult. The pathogenesis of bullae formation in morphea is multifactorial, but reactive oxygen species production appears to play a key role. We report a patient with bu...

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Veröffentlicht in:International journal of immunopathology and pharmacology 2013, Vol.26 (1), p.259-262
Hauptverfasser: Rosato, E, Veneziano, M L, Di Mario, A, Molinaro, I, Pisarri, S, Salsano, F
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Sprache:eng
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container_title International journal of immunopathology and pharmacology
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creator Rosato, E
Veneziano, M L
Di Mario, A
Molinaro, I
Pisarri, S
Salsano, F
description Bullous morphea is an uncommon form of localized scleroderma. The pathogenesis is unknown and treatment of coexistent ulcers is difficult. The pathogenesis of bullae formation in morphea is multifactorial, but reactive oxygen species production appears to play a key role. We report a patient with bullous morphea with long-standing ulcers whom we successfully treated with N-acetylcysteine and topical wound care. N-acetylcysteine, an antioxidant sulfhydryl substance, promotes the healing of ulcers in patients with bullous morphea.
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title Ulcers caused by bullous morphea: successful therapy with N-acetylcysteine and topical wound care
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