Longitudinal compression of the platinum-chromium everolimus-eluting stent during coronary implantation: Predisposing mechanical properties, incidence, and predictors in a large patient cohort
Objectives: To assess the longitudinal compression behavior of platinum‐chromium everolimus‐eluting stents, evaluate frequency of inadvertent longitudinal compression during percutaneous intervention, and define patient‐ and lesion‐related predictors of this complication. Background: Platinum‐chromi...
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Veröffentlicht in: | Catheterization and cardiovascular interventions 2013-04, Vol.81 (5), p.E206-E214 |
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description | Objectives: To assess the longitudinal compression behavior of platinum‐chromium everolimus‐eluting stents, evaluate frequency of inadvertent longitudinal compression during percutaneous intervention, and define patient‐ and lesion‐related predictors of this complication. Background: Platinum‐chromium stents of Element family have unique design features to improve flexibility that may, however, impair longitudinal stability. Incidence of longitudinal stent compression during implantation and predictors for this complication are not well understood. Methods: Five contemporary stent platforms were longitudinally compressed in a bench test experiment, and spring constant, yield force, and ultimate strength were calculated from force‐strain curves. We also evaluated all coronary cases treated with an Element stent from January 1, 2010, to October 31, 2011, for documented longitudinal compression. We compared baseline characteristics and periprocedural data between patients with and without longitudinal stent compression and assessed predictors for this event by multiple logistic regression models. Results: Yield force and ultimate strength were significantly lower for the Element compared with all other tested stents. In 20 patients (1.4%) and 20 lesions (0.7%) from 1,392 cases with 2,839 atherosclerotic lesions longitudinal stent compression was reported. Ostial segments, number of stents, and the presence of a bifurcation were significant predictors (adjusted odds ratios [95% confidence intervals]: 8.33 [3.30–21.28], 1.57 [1.01–2.45], 3.57 [1.36–9.35], respectively). Conclusion: The Element stent exhibits the lowest overall longitudinal strength compared with four contemporary platforms. Longitudinal compression of the Element stent is a rare complication and occurs more frequently in ostial or bifurcation lesions and with multiple stents. © 2012 Wiley Periodicals, Inc. |
doi_str_mv | 10.1002/ccd.24472 |
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Background: Platinum‐chromium stents of Element family have unique design features to improve flexibility that may, however, impair longitudinal stability. Incidence of longitudinal stent compression during implantation and predictors for this complication are not well understood. Methods: Five contemporary stent platforms were longitudinally compressed in a bench test experiment, and spring constant, yield force, and ultimate strength were calculated from force‐strain curves. We also evaluated all coronary cases treated with an Element stent from January 1, 2010, to October 31, 2011, for documented longitudinal compression. We compared baseline characteristics and periprocedural data between patients with and without longitudinal stent compression and assessed predictors for this event by multiple logistic regression models. Results: Yield force and ultimate strength were significantly lower for the Element compared with all other tested stents. In 20 patients (1.4%) and 20 lesions (0.7%) from 1,392 cases with 2,839 atherosclerotic lesions longitudinal stent compression was reported. Ostial segments, number of stents, and the presence of a bifurcation were significant predictors (adjusted odds ratios [95% confidence intervals]: 8.33 [3.30–21.28], 1.57 [1.01–2.45], 3.57 [1.36–9.35], respectively). Conclusion: The Element stent exhibits the lowest overall longitudinal strength compared with four contemporary platforms. Longitudinal compression of the Element stent is a rare complication and occurs more frequently in ostial or bifurcation lesions and with multiple stents. © 2012 Wiley Periodicals, Inc.</description><identifier>ISSN: 1522-1946</identifier><identifier>EISSN: 1522-726X</identifier><identifier>DOI: 10.1002/ccd.24472</identifier><identifier>PMID: 22581708</identifier><identifier>CODEN: CARIF2</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Aged ; Cardiovascular Agents - administration & dosage ; Chi-Square Distribution ; Chromium ; complications adult cath/intervention ; Coronary Angiography ; coronary artery disease ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - therapy ; Drug-Eluting Stents ; Equipment Failure Analysis ; Everolimus ; Female ; Humans ; Logistic Models ; Male ; Materials Testing ; Middle Aged ; Multivariate Analysis ; Odds Ratio ; percutaneous coronary intervention ; Percutaneous Coronary Intervention - adverse effects ; Percutaneous Coronary Intervention - instrumentation ; Platinum ; Prosthesis Design ; Prosthesis Failure ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Sirolimus - administration & dosage ; Sirolimus - analogs & derivatives ; stent structure ; Stress, Mechanical ; Tomography, Optical Coherence ; Treatment Outcome</subject><ispartof>Catheterization and cardiovascular interventions, 2013-04, Vol.81 (5), p.E206-E214</ispartof><rights>Copyright © 2012 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3912-b83e5e4977655a6b148ac584c81fc670a7dd4b1fa820ba792a9bc80878fa205e3</citedby><cites>FETCH-LOGICAL-c3912-b83e5e4977655a6b148ac584c81fc670a7dd4b1fa820ba792a9bc80878fa205e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fccd.24472$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fccd.24472$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22581708$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leibundgut, Gregor</creatorcontrib><creatorcontrib>Gick, Michael</creatorcontrib><creatorcontrib>Toma, Aurel</creatorcontrib><creatorcontrib>Valina, Christian</creatorcontrib><creatorcontrib>Löffelhardt, Nikolaus</creatorcontrib><creatorcontrib>Joachim Büttner, Heinz</creatorcontrib><creatorcontrib>Neumann, Franz-Josef</creatorcontrib><title>Longitudinal compression of the platinum-chromium everolimus-eluting stent during coronary implantation: Predisposing mechanical properties, incidence, and predictors in a large patient cohort</title><title>Catheterization and cardiovascular interventions</title><addtitle>Cathet. Cardiovasc. Intervent</addtitle><description>Objectives: To assess the longitudinal compression behavior of platinum‐chromium everolimus‐eluting stents, evaluate frequency of inadvertent longitudinal compression during percutaneous intervention, and define patient‐ and lesion‐related predictors of this complication. Background: Platinum‐chromium stents of Element family have unique design features to improve flexibility that may, however, impair longitudinal stability. Incidence of longitudinal stent compression during implantation and predictors for this complication are not well understood. Methods: Five contemporary stent platforms were longitudinally compressed in a bench test experiment, and spring constant, yield force, and ultimate strength were calculated from force‐strain curves. We also evaluated all coronary cases treated with an Element stent from January 1, 2010, to October 31, 2011, for documented longitudinal compression. We compared baseline characteristics and periprocedural data between patients with and without longitudinal stent compression and assessed predictors for this event by multiple logistic regression models. Results: Yield force and ultimate strength were significantly lower for the Element compared with all other tested stents. In 20 patients (1.4%) and 20 lesions (0.7%) from 1,392 cases with 2,839 atherosclerotic lesions longitudinal stent compression was reported. Ostial segments, number of stents, and the presence of a bifurcation were significant predictors (adjusted odds ratios [95% confidence intervals]: 8.33 [3.30–21.28], 1.57 [1.01–2.45], 3.57 [1.36–9.35], respectively). Conclusion: The Element stent exhibits the lowest overall longitudinal strength compared with four contemporary platforms. Longitudinal compression of the Element stent is a rare complication and occurs more frequently in ostial or bifurcation lesions and with multiple stents. © 2012 Wiley Periodicals, Inc.</description><subject>Aged</subject><subject>Cardiovascular Agents - administration & dosage</subject><subject>Chi-Square Distribution</subject><subject>Chromium</subject><subject>complications adult cath/intervention</subject><subject>Coronary Angiography</subject><subject>coronary artery disease</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - therapy</subject><subject>Drug-Eluting Stents</subject><subject>Equipment Failure Analysis</subject><subject>Everolimus</subject><subject>Female</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Materials Testing</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Odds Ratio</subject><subject>percutaneous coronary intervention</subject><subject>Percutaneous Coronary Intervention - adverse effects</subject><subject>Percutaneous Coronary Intervention - instrumentation</subject><subject>Platinum</subject><subject>Prosthesis Design</subject><subject>Prosthesis Failure</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Sirolimus - administration & dosage</subject><subject>Sirolimus - analogs & derivatives</subject><subject>stent structure</subject><subject>Stress, Mechanical</subject><subject>Tomography, Optical Coherence</subject><subject>Treatment Outcome</subject><issn>1522-1946</issn><issn>1522-726X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kcFu1DAQhiNERUvhwAsgS1xAalrbiWOnN7RAqbQqHArtzXKcya5LbAc7Bvp2PBre7rYHpJ5sa77_n_H8RfGK4GOCMT3Ruj-mdc3pk-KAMEpLTpvrp7s7aetmv3ge4w3GuG1o-6zYp5QJwrE4KP4uvVuZOfXGqRFpb6cAMRrvkB_QvAY0jWo2LtlSr4O3JlkEvyD40dgUSxhTLq5QnMHNqE9h89A-eKfCLTI2i92c9d6doq8BehMnHzeMBb1Wzujccwp-gjAbiEfIOG16cBqOkHJ9LmWJnn2IuYIUGlVY5Ymy4aad9msf5hfF3qDGCC9352Hx7dPHy8Xncvnl7HzxflnqqiW07EQFDOqW84Yx1XSkFkozUWtBBt1wrHjf1x0ZlKC4U7ylqu20wIKLQVHMoDos3m5987w_E8RZWhM1jPmH4FOUpCJtU1W14Bl98x9641PI-72jhOCMEZypd1tKBx9jgEFOwdi8N0mw3MQqc6zyLtbMvt45ps5C_0De55iBky3w24xw-7iTXCw-3FuWW4XJ4f15UKjwQza84kxeXZzJ7-ySX181RPLqHws6wGw</recordid><startdate>201304</startdate><enddate>201304</enddate><creator>Leibundgut, Gregor</creator><creator>Gick, Michael</creator><creator>Toma, Aurel</creator><creator>Valina, Christian</creator><creator>Löffelhardt, Nikolaus</creator><creator>Joachim Büttner, Heinz</creator><creator>Neumann, Franz-Josef</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201304</creationdate><title>Longitudinal compression of the platinum-chromium everolimus-eluting stent during coronary implantation: Predisposing mechanical properties, incidence, and predictors in a large patient cohort</title><author>Leibundgut, Gregor ; Gick, Michael ; Toma, Aurel ; Valina, Christian ; Löffelhardt, Nikolaus ; Joachim Büttner, Heinz ; Neumann, Franz-Josef</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3912-b83e5e4977655a6b148ac584c81fc670a7dd4b1fa820ba792a9bc80878fa205e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Cardiovascular Agents - administration & dosage</topic><topic>Chi-Square Distribution</topic><topic>Chromium</topic><topic>complications adult cath/intervention</topic><topic>Coronary Angiography</topic><topic>coronary artery disease</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - therapy</topic><topic>Drug-Eluting Stents</topic><topic>Equipment Failure Analysis</topic><topic>Everolimus</topic><topic>Female</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Materials Testing</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Odds Ratio</topic><topic>percutaneous coronary intervention</topic><topic>Percutaneous Coronary Intervention - adverse effects</topic><topic>Percutaneous Coronary Intervention - instrumentation</topic><topic>Platinum</topic><topic>Prosthesis Design</topic><topic>Prosthesis Failure</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Sirolimus - administration & dosage</topic><topic>Sirolimus - analogs & derivatives</topic><topic>stent structure</topic><topic>Stress, Mechanical</topic><topic>Tomography, Optical Coherence</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leibundgut, Gregor</creatorcontrib><creatorcontrib>Gick, Michael</creatorcontrib><creatorcontrib>Toma, Aurel</creatorcontrib><creatorcontrib>Valina, Christian</creatorcontrib><creatorcontrib>Löffelhardt, Nikolaus</creatorcontrib><creatorcontrib>Joachim Büttner, Heinz</creatorcontrib><creatorcontrib>Neumann, Franz-Josef</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leibundgut, Gregor</au><au>Gick, Michael</au><au>Toma, Aurel</au><au>Valina, Christian</au><au>Löffelhardt, Nikolaus</au><au>Joachim Büttner, Heinz</au><au>Neumann, Franz-Josef</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Longitudinal compression of the platinum-chromium everolimus-eluting stent during coronary implantation: Predisposing mechanical properties, incidence, and predictors in a large patient cohort</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><addtitle>Cathet. Cardiovasc. Intervent</addtitle><date>2013-04</date><risdate>2013</risdate><volume>81</volume><issue>5</issue><spage>E206</spage><epage>E214</epage><pages>E206-E214</pages><issn>1522-1946</issn><eissn>1522-726X</eissn><coden>CARIF2</coden><abstract>Objectives: To assess the longitudinal compression behavior of platinum‐chromium everolimus‐eluting stents, evaluate frequency of inadvertent longitudinal compression during percutaneous intervention, and define patient‐ and lesion‐related predictors of this complication. Background: Platinum‐chromium stents of Element family have unique design features to improve flexibility that may, however, impair longitudinal stability. Incidence of longitudinal stent compression during implantation and predictors for this complication are not well understood. Methods: Five contemporary stent platforms were longitudinally compressed in a bench test experiment, and spring constant, yield force, and ultimate strength were calculated from force‐strain curves. We also evaluated all coronary cases treated with an Element stent from January 1, 2010, to October 31, 2011, for documented longitudinal compression. We compared baseline characteristics and periprocedural data between patients with and without longitudinal stent compression and assessed predictors for this event by multiple logistic regression models. Results: Yield force and ultimate strength were significantly lower for the Element compared with all other tested stents. In 20 patients (1.4%) and 20 lesions (0.7%) from 1,392 cases with 2,839 atherosclerotic lesions longitudinal stent compression was reported. Ostial segments, number of stents, and the presence of a bifurcation were significant predictors (adjusted odds ratios [95% confidence intervals]: 8.33 [3.30–21.28], 1.57 [1.01–2.45], 3.57 [1.36–9.35], respectively). Conclusion: The Element stent exhibits the lowest overall longitudinal strength compared with four contemporary platforms. Longitudinal compression of the Element stent is a rare complication and occurs more frequently in ostial or bifurcation lesions and with multiple stents. © 2012 Wiley Periodicals, Inc.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>22581708</pmid><doi>10.1002/ccd.24472</doi><tpages>9</tpages></addata></record> |
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subjects | Aged Cardiovascular Agents - administration & dosage Chi-Square Distribution Chromium complications adult cath/intervention Coronary Angiography coronary artery disease Coronary Artery Disease - diagnosis Coronary Artery Disease - therapy Drug-Eluting Stents Equipment Failure Analysis Everolimus Female Humans Logistic Models Male Materials Testing Middle Aged Multivariate Analysis Odds Ratio percutaneous coronary intervention Percutaneous Coronary Intervention - adverse effects Percutaneous Coronary Intervention - instrumentation Platinum Prosthesis Design Prosthesis Failure Retrospective Studies Risk Assessment Risk Factors Sirolimus - administration & dosage Sirolimus - analogs & derivatives stent structure Stress, Mechanical Tomography, Optical Coherence Treatment Outcome |
title | Longitudinal compression of the platinum-chromium everolimus-eluting stent during coronary implantation: Predisposing mechanical properties, incidence, and predictors in a large patient cohort |
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