Screening soy hydrolysates for the production of a recombinant therapeutic protein in commercial cell line by combined approach of near-infrared spectroscopy and chemometrics

Soy hydrolysates are widely used as the major nutrient sources for cell culture processes for industrial manufacturing of therapeutic recombinant proteins. The primary goal of this study was to develop a spectroscopy based chemometric method, a partial least squares (PLS), to screen soy hydrolysates...

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Veröffentlicht in:Applied microbiology and biotechnology 2013-03, Vol.97 (6), p.2653-2660
Hauptverfasser: Li, Guiyang, Wen, Zai-qing
Format: Artikel
Sprache:eng
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