Prolapse-related changes are a confounding factor in misdiagnosis of sessile serrated adenomas in the rectum

Summary The differential diagnosis of rectal serrated polyps is challenging due to its unique anatomic location, the evolving concept of serrated polyps over the past several years, and to histologic changes seen in rectal mucosal prolapse. We reclassified 95 rectal polyps diagnosed originally as “s...

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Veröffentlicht in:	Human pathology 2013-04, Vol.44 (4), p.480-486
Hauptverfasser:	Huang, Cheng Cheng, MD, PhD, Frankel, Wendy L., MD, Doukides, Theodore, MD, Zhou, Xiao-Ping, MD, PhD, Zhao, Weiqiang, MD, PhD, Yearsley, Martha M., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - diagnosis Adenoma - epidemiology Adenoma - genetics Adult Aged Aged, 80 and over BRAF V600E mutation Colon Colonic Polyps - diagnosis Colonic Polyps - epidemiology Colonic Polyps - genetics Colorectal cancer Comorbidity Confounding Factors (Epidemiology) Diagnosis Diagnosis, Differential Diagnostic Errors DNA methylation DNA Mutational Analysis DNA, Neoplasm - analysis Female Humans Hyperplasia Male Middle Aged Mutation Pathology Proteins Proto-Oncogene Proteins B-raf - genetics Rectal Neoplasms - diagnosis Rectal Neoplasms - epidemiology Rectal Neoplasms - genetics Rectal Prolapse - diagnosis Rectal Prolapse - epidemiology Rectal Prolapse - genetics Rectum Serrated polyp World Health Organization
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