Preventive effect of sivelestat on postoperative respiratory disorders after thoracic esophagectomy

Purpose Sivelestat, a selective inhibitor of neutrophil elastase, has been reported to reduce acute lung injury associated with systemic inflammatory response syndrome. This study retrospectively investigated the effect of sivelestat on respiratory function in patients who underwent esophagectomy. M...

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Veröffentlicht in:	Surgery today (Tokyo, Japan) Japan), 2013-04, Vol.43 (4), p.361-366
Hauptverfasser:	Nagai, Yohei, Watanabe, Masayuki, Baba, Yoshihumi, Iwatsuki, Masaaki, Hirashima, Kotaro, Karashima, Ryuichi, Kurashige, Jyunji, Kinoshita, Koichi, Baba, Hideo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - diagnosis Acute Lung Injury - etiology Acute Lung Injury - prevention & control Adult Aged Aged, 80 and over Anti-Inflammatory Agents - therapeutic use Drug Administration Schedule Drug Therapy, Combination Esophageal Neoplasms - surgery Esophagectomy Female Glycine - analogs & derivatives Glycine - therapeutic use Humans Intraoperative Care Male Medicine Medicine & Public Health Methylprednisolone - therapeutic use Middle Aged Original Article Postoperative Care Postoperative Complications - diagnosis Postoperative Complications - prevention & control Respiratory Distress Syndrome, Adult - diagnosis Respiratory Distress Syndrome, Adult - etiology Respiratory Distress Syndrome, Adult - prevention & control Respiratory Function Tests Retrospective Studies Serine Proteinase Inhibitors - therapeutic use Sulfonamides - therapeutic use Surgery Surgical Oncology Systemic Inflammatory Response Syndrome - diagnosis Systemic Inflammatory Response Syndrome - etiology Systemic Inflammatory Response Syndrome - prevention & control Treatment Outcome
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