Usefulness of Dual and Fully Automated Measurements of Cerebral Blood Flow during Balloon Occlusion Test of the Internal Carotid Artery
Background This study was conducted to show the reliability of fully automated quantification of regional cerebral blood flow (rCBF) in balloon occlusion test (BOT) of the internal carotid artery (ICA). We also shows the usefulness of ratio of rCBF during BOT to rCBF at rest (BOT/rest ratio = rCBF d...
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| creator | Torigai, Takeshi, MD Mase, Mitsuhito, MD, PhD Ohno, Takayuki, MD Katano, Hiroyuki, MD, PhD Nisikawa, Yusuke, MD Sakurai, Keita, MD Sasaki, Shigeru, MD Toyama, Junko, MD Yamada, Kazuo, MD, PhD |
| description | Background This study was conducted to show the reliability of fully automated quantification of regional cerebral blood flow (rCBF) in balloon occlusion test (BOT) of the internal carotid artery (ICA). We also shows the usefulness of ratio of rCBF during BOT to rCBF at rest (BOT/rest ratio = rCBF during BOT/rCBF at rest) rather than asymmetry index (AI) during BOT (AI = occluded-side rCBF/contralateral rCBF). Methods In the last 2 years, we performed the BOT on 10 consecutive patients (4 with intracranial aneurysms and 6 with head and neck tumors). During the BOT, mean stump pressure (MSTP) of the ICA was monitored. We measured cerebral blood flow (CBF) with technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography at rest and during BOT. rCBF was determined using 3-dimensional stereotaxic region of interest template (3DSRT) which automatically divided CBF into 12 segments. We defined hypoperfusion segment as BOT/rest ratio |
| doi_str_mv | 10.1016/j.jstrokecerebrovasdis.2011.07.015 |
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We also shows the usefulness of ratio of rCBF during BOT to rCBF at rest (BOT/rest ratio = rCBF during BOT/rCBF at rest) rather than asymmetry index (AI) during BOT (AI = occluded-side rCBF/contralateral rCBF). Methods In the last 2 years, we performed the BOT on 10 consecutive patients (4 with intracranial aneurysms and 6 with head and neck tumors). During the BOT, mean stump pressure (MSTP) of the ICA was monitored. We measured cerebral blood flow (CBF) with technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography at rest and during BOT. rCBF was determined using 3-dimensional stereotaxic region of interest template (3DSRT) which automatically divided CBF into 12 segments. We defined hypoperfusion segment as BOT/rest ratio <0.9 or AI <0.9. Results When the BOT/rest ratio was used as a hypoperfusion parameter, the number of hypoperfusion segments was significantly greater in patients with an MSTP ≤50 mm Hg than in patients with an MSTP >50 mm Hg. However, only AI during BOT did not reflect MSTP significantly. Conclusions The evaluation of CBF changes in BOT using 3DSRT and the BOT/rest ratio were useful because of objective comparison.</description><identifier>ISSN: 1052-3057</identifier><identifier>EISSN: 1532-8511</identifier><identifier>DOI: 10.1016/j.jstrokecerebrovasdis.2011.07.015</identifier><identifier>PMID: 21930394</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>3-dimensional stereotactic region of interest template ; Adult ; Aged ; Automation ; Balloon Occlusion ; Balloon occlusion test ; Cardiovascular ; Carotid Artery Diseases - diagnosis ; Carotid Artery Diseases - diagnostic imaging ; Carotid Artery Diseases - physiopathology ; Carotid Artery, Internal - diagnostic imaging ; Carotid Artery, Internal - physiopathology ; cerebral blood flow ; Cerebrovascular Circulation ; Diagnostic Techniques, Cardiovascular ; dual single-photon emission computed tomography ; Female ; Hemodynamics ; Humans ; Image Interpretation, Computer-Assisted ; Imaging, Three-Dimensional ; Intracranial Aneurysm - diagnosis ; Intracranial Aneurysm - diagnostic imaging ; Intracranial Aneurysm - physiopathology ; Male ; mean stump pressure ; Middle Aged ; Multimodal Imaging ; Neoplasm Invasiveness ; Neurology ; Positron-Emission Tomography ; Predictive Value of Tests ; Radiopharmaceuticals ; Reproducibility of Results ; Technetium Tc 99m Exametazime ; technetium-99m hexamethylpropylene amine oxime ; Tomography, X-Ray Computed</subject><ispartof>Journal of stroke and cerebrovascular diseases, 2013-04, Vol.22 (3), p.197-204</ispartof><rights>National Stroke Association</rights><rights>2013 National Stroke Association</rights><rights>Copyright © 2013 National Stroke Association. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-af6e3c797a8ca188557cfbbac5102721baeffc1b679cd935b6b9f34cb0559bbd3</citedby><cites>FETCH-LOGICAL-c525t-af6e3c797a8ca188557cfbbac5102721baeffc1b679cd935b6b9f34cb0559bbd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1052305711002229$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21930394$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Torigai, Takeshi, MD</creatorcontrib><creatorcontrib>Mase, Mitsuhito, MD, PhD</creatorcontrib><creatorcontrib>Ohno, Takayuki, MD</creatorcontrib><creatorcontrib>Katano, Hiroyuki, MD, PhD</creatorcontrib><creatorcontrib>Nisikawa, Yusuke, MD</creatorcontrib><creatorcontrib>Sakurai, Keita, MD</creatorcontrib><creatorcontrib>Sasaki, Shigeru, MD</creatorcontrib><creatorcontrib>Toyama, Junko, MD</creatorcontrib><creatorcontrib>Yamada, Kazuo, MD, PhD</creatorcontrib><title>Usefulness of Dual and Fully Automated Measurements of Cerebral Blood Flow during Balloon Occlusion Test of the Internal Carotid Artery</title><title>Journal of stroke and cerebrovascular diseases</title><addtitle>J Stroke Cerebrovasc Dis</addtitle><description>Background This study was conducted to show the reliability of fully automated quantification of regional cerebral blood flow (rCBF) in balloon occlusion test (BOT) of the internal carotid artery (ICA). We also shows the usefulness of ratio of rCBF during BOT to rCBF at rest (BOT/rest ratio = rCBF during BOT/rCBF at rest) rather than asymmetry index (AI) during BOT (AI = occluded-side rCBF/contralateral rCBF). Methods In the last 2 years, we performed the BOT on 10 consecutive patients (4 with intracranial aneurysms and 6 with head and neck tumors). During the BOT, mean stump pressure (MSTP) of the ICA was monitored. We measured cerebral blood flow (CBF) with technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography at rest and during BOT. rCBF was determined using 3-dimensional stereotaxic region of interest template (3DSRT) which automatically divided CBF into 12 segments. We defined hypoperfusion segment as BOT/rest ratio <0.9 or AI <0.9. Results When the BOT/rest ratio was used as a hypoperfusion parameter, the number of hypoperfusion segments was significantly greater in patients with an MSTP ≤50 mm Hg than in patients with an MSTP >50 mm Hg. However, only AI during BOT did not reflect MSTP significantly. Conclusions The evaluation of CBF changes in BOT using 3DSRT and the BOT/rest ratio were useful because of objective comparison.</description><subject>3-dimensional stereotactic region of interest template</subject><subject>Adult</subject><subject>Aged</subject><subject>Automation</subject><subject>Balloon Occlusion</subject><subject>Balloon occlusion test</subject><subject>Cardiovascular</subject><subject>Carotid Artery Diseases - diagnosis</subject><subject>Carotid Artery Diseases - diagnostic imaging</subject><subject>Carotid Artery Diseases - physiopathology</subject><subject>Carotid Artery, Internal - diagnostic imaging</subject><subject>Carotid Artery, Internal - physiopathology</subject><subject>cerebral blood flow</subject><subject>Cerebrovascular Circulation</subject><subject>Diagnostic Techniques, Cardiovascular</subject><subject>dual single-photon emission computed tomography</subject><subject>Female</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted</subject><subject>Imaging, Three-Dimensional</subject><subject>Intracranial Aneurysm - diagnosis</subject><subject>Intracranial Aneurysm - diagnostic imaging</subject><subject>Intracranial Aneurysm - physiopathology</subject><subject>Male</subject><subject>mean stump pressure</subject><subject>Middle Aged</subject><subject>Multimodal Imaging</subject><subject>Neoplasm Invasiveness</subject><subject>Neurology</subject><subject>Positron-Emission Tomography</subject><subject>Predictive Value of Tests</subject><subject>Radiopharmaceuticals</subject><subject>Reproducibility of Results</subject><subject>Technetium Tc 99m Exametazime</subject><subject>technetium-99m hexamethylpropylene amine oxime</subject><subject>Tomography, X-Ray Computed</subject><issn>1052-3057</issn><issn>1532-8511</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVksluFDEQhlsIRELgFZCPCKk7XuJeLkgzE0IiDcqB5Gx5qQZ3PO3gJWiegNfGnQkcEBdOLpW--qvKf1XVe4Ibgkl7OjVTTMHfgYYAKvgHGY2NDcWENLhrMOHPqmPCGa17TsjzEmNOa4Z5d1S9inHCBeQ9f1kdUTIwzIaz4-rnbYQxuxliRH5E51k6JGeDLrJze7TKye9kAoM-g4w5wA7m9AhuHkco8Np5X3DnfyCTg52_orV0JTeja61djrZENxDTUpS-AbqaE4S5FG5k8MkatAolsX9dvRili_Dm6T2pbi8-3mwu6-31p6vNaltrTnmq5dgC093QyV5L0vecd3pUSmpOMO0oURLGURPVdoM2A-OqVcPIzrTCnA9KGXZSvTvo3gf_PZe5xM5GDc7JGXyOgjDSFdWhawu6PqA6-BgDjOI-2J0Me0GwWAwRk_iXIWIxROBOFEOKyNunflntwPyR-O1AAbYHAMrWDxaCiNrCrMHYADoJ4-3_9fvwl5x2drZaujvYQ5x8Xj6_7CkiFVh8WU5kuRBCMKaUDuwXa8LChg</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>Torigai, Takeshi, MD</creator><creator>Mase, Mitsuhito, MD, PhD</creator><creator>Ohno, Takayuki, MD</creator><creator>Katano, Hiroyuki, MD, PhD</creator><creator>Nisikawa, Yusuke, MD</creator><creator>Sakurai, Keita, MD</creator><creator>Sasaki, Shigeru, MD</creator><creator>Toyama, Junko, MD</creator><creator>Yamada, Kazuo, MD, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130401</creationdate><title>Usefulness of Dual and Fully Automated Measurements of Cerebral Blood Flow during Balloon Occlusion Test of the Internal Carotid Artery</title><author>Torigai, Takeshi, MD ; Mase, Mitsuhito, MD, PhD ; Ohno, Takayuki, MD ; Katano, Hiroyuki, MD, PhD ; Nisikawa, Yusuke, MD ; Sakurai, Keita, MD ; Sasaki, Shigeru, MD ; Toyama, Junko, MD ; Yamada, Kazuo, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-af6e3c797a8ca188557cfbbac5102721baeffc1b679cd935b6b9f34cb0559bbd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>3-dimensional stereotactic region of interest template</topic><topic>Adult</topic><topic>Aged</topic><topic>Automation</topic><topic>Balloon Occlusion</topic><topic>Balloon occlusion test</topic><topic>Cardiovascular</topic><topic>Carotid Artery Diseases - diagnosis</topic><topic>Carotid Artery Diseases - diagnostic imaging</topic><topic>Carotid Artery Diseases - physiopathology</topic><topic>Carotid Artery, Internal - diagnostic imaging</topic><topic>Carotid Artery, Internal - physiopathology</topic><topic>cerebral blood flow</topic><topic>Cerebrovascular Circulation</topic><topic>Diagnostic Techniques, Cardiovascular</topic><topic>dual single-photon emission computed tomography</topic><topic>Female</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Image Interpretation, Computer-Assisted</topic><topic>Imaging, Three-Dimensional</topic><topic>Intracranial Aneurysm - diagnosis</topic><topic>Intracranial Aneurysm - diagnostic imaging</topic><topic>Intracranial Aneurysm - physiopathology</topic><topic>Male</topic><topic>mean stump pressure</topic><topic>Middle Aged</topic><topic>Multimodal Imaging</topic><topic>Neoplasm Invasiveness</topic><topic>Neurology</topic><topic>Positron-Emission Tomography</topic><topic>Predictive Value of Tests</topic><topic>Radiopharmaceuticals</topic><topic>Reproducibility of Results</topic><topic>Technetium Tc 99m Exametazime</topic><topic>technetium-99m hexamethylpropylene amine oxime</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Torigai, Takeshi, MD</creatorcontrib><creatorcontrib>Mase, Mitsuhito, MD, PhD</creatorcontrib><creatorcontrib>Ohno, Takayuki, MD</creatorcontrib><creatorcontrib>Katano, Hiroyuki, MD, PhD</creatorcontrib><creatorcontrib>Nisikawa, Yusuke, MD</creatorcontrib><creatorcontrib>Sakurai, Keita, MD</creatorcontrib><creatorcontrib>Sasaki, Shigeru, MD</creatorcontrib><creatorcontrib>Toyama, Junko, MD</creatorcontrib><creatorcontrib>Yamada, Kazuo, MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of stroke and cerebrovascular diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Torigai, Takeshi, MD</au><au>Mase, Mitsuhito, MD, PhD</au><au>Ohno, Takayuki, MD</au><au>Katano, Hiroyuki, MD, PhD</au><au>Nisikawa, Yusuke, MD</au><au>Sakurai, Keita, MD</au><au>Sasaki, Shigeru, MD</au><au>Toyama, Junko, MD</au><au>Yamada, Kazuo, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Usefulness of Dual and Fully Automated Measurements of Cerebral Blood Flow during Balloon Occlusion Test of the Internal Carotid Artery</atitle><jtitle>Journal of stroke and cerebrovascular diseases</jtitle><addtitle>J Stroke Cerebrovasc Dis</addtitle><date>2013-04-01</date><risdate>2013</risdate><volume>22</volume><issue>3</issue><spage>197</spage><epage>204</epage><pages>197-204</pages><issn>1052-3057</issn><eissn>1532-8511</eissn><abstract>Background This study was conducted to show the reliability of fully automated quantification of regional cerebral blood flow (rCBF) in balloon occlusion test (BOT) of the internal carotid artery (ICA). We also shows the usefulness of ratio of rCBF during BOT to rCBF at rest (BOT/rest ratio = rCBF during BOT/rCBF at rest) rather than asymmetry index (AI) during BOT (AI = occluded-side rCBF/contralateral rCBF). Methods In the last 2 years, we performed the BOT on 10 consecutive patients (4 with intracranial aneurysms and 6 with head and neck tumors). During the BOT, mean stump pressure (MSTP) of the ICA was monitored. We measured cerebral blood flow (CBF) with technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography at rest and during BOT. rCBF was determined using 3-dimensional stereotaxic region of interest template (3DSRT) which automatically divided CBF into 12 segments. We defined hypoperfusion segment as BOT/rest ratio <0.9 or AI <0.9. Results When the BOT/rest ratio was used as a hypoperfusion parameter, the number of hypoperfusion segments was significantly greater in patients with an MSTP ≤50 mm Hg than in patients with an MSTP >50 mm Hg. However, only AI during BOT did not reflect MSTP significantly. Conclusions The evaluation of CBF changes in BOT using 3DSRT and the BOT/rest ratio were useful because of objective comparison.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>21930394</pmid><doi>10.1016/j.jstrokecerebrovasdis.2011.07.015</doi><tpages>8</tpages></addata></record> |
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| subjects | 3-dimensional stereotactic region of interest template Adult Aged Automation Balloon Occlusion Balloon occlusion test Cardiovascular Carotid Artery Diseases - diagnosis Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - physiopathology Carotid Artery, Internal - diagnostic imaging Carotid Artery, Internal - physiopathology cerebral blood flow Cerebrovascular Circulation Diagnostic Techniques, Cardiovascular dual single-photon emission computed tomography Female Hemodynamics Humans Image Interpretation, Computer-Assisted Imaging, Three-Dimensional Intracranial Aneurysm - diagnosis Intracranial Aneurysm - diagnostic imaging Intracranial Aneurysm - physiopathology Male mean stump pressure Middle Aged Multimodal Imaging Neoplasm Invasiveness Neurology Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Reproducibility of Results Technetium Tc 99m Exametazime technetium-99m hexamethylpropylene amine oxime Tomography, X-Ray Computed |
| title | Usefulness of Dual and Fully Automated Measurements of Cerebral Blood Flow during Balloon Occlusion Test of the Internal Carotid Artery |
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