The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage
Abstract Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would res...
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| Veröffentlicht in: | The Journal of arthroplasty 2013-04, Vol.28 (4), p.553-556 |
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| container_title | The Journal of arthroplasty |
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| creator | El-Gazzar, Yaser, MD Smith, Daniel C., MD Kim, Sun Jin, MD Hirsh, David M., MD Blum, Yossef, MD Cobelli, Marcie, FNP Cohen, Hillel W., DrPH, MPH |
| description | Abstract Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann–Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level ( P < 0.001). |
| doi_str_mv | 10.1016/j.arth.2012.07.038 |
| format | Article |
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This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann–Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level ( P < 0.001).</description><identifier>ISSN: 0883-5403</identifier><identifier>EISSN: 1532-8406</identifier><identifier>DOI: 10.1016/j.arth.2012.07.038</identifier><identifier>PMID: 23114193</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Arthroplasty, Replacement, Knee - methods ; Cyanoacrylates ; dermabond ; Drainage ; Female ; Humans ; Male ; Middle Aged ; Orthopedics ; Postoperative Period ; Prospective Studies ; Single-Blind Method ; Time Factors ; Tissue Adhesives ; total knee arthroplasty ; Wound Closure Techniques ; Wound Healing</subject><ispartof>The Journal of arthroplasty, 2013-04, Vol.28 (4), p.553-556</ispartof><rights>Elsevier Inc.</rights><rights>2013 Elsevier Inc.</rights><rights>Copyright © 2013 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-a217ca02d639fa88928e97ae0b4320da0837bc9cba562f3b06ccd1c5fbb3b3353</citedby><cites>FETCH-LOGICAL-c411t-a217ca02d639fa88928e97ae0b4320da0837bc9cba562f3b06ccd1c5fbb3b3353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.arth.2012.07.038$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23114193$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El-Gazzar, Yaser, MD</creatorcontrib><creatorcontrib>Smith, Daniel C., MD</creatorcontrib><creatorcontrib>Kim, Sun Jin, MD</creatorcontrib><creatorcontrib>Hirsh, David M., MD</creatorcontrib><creatorcontrib>Blum, Yossef, MD</creatorcontrib><creatorcontrib>Cobelli, Marcie, FNP</creatorcontrib><creatorcontrib>Cohen, Hillel W., DrPH, MPH</creatorcontrib><title>The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage</title><title>The Journal of arthroplasty</title><addtitle>J Arthroplasty</addtitle><description>Abstract Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann–Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level ( P < 0.001).</description><subject>Aged</subject><subject>Arthroplasty, Replacement, Knee - methods</subject><subject>Cyanoacrylates</subject><subject>dermabond</subject><subject>Drainage</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Orthopedics</subject><subject>Postoperative Period</subject><subject>Prospective Studies</subject><subject>Single-Blind Method</subject><subject>Time Factors</subject><subject>Tissue Adhesives</subject><subject>total knee arthroplasty</subject><subject>Wound Closure Techniques</subject><subject>Wound Healing</subject><issn>0883-5403</issn><issn>1532-8406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk1u1EAQhVsIRIbABVigXrKx0z_-RQhpNAkhIlKQmIhlq9wuJzZ299DdjpgLcBwOwcloawYWLFiVVHrvqerTI-QlZylnvDgbUnDhPhWMi5SVKZPVI7LiuRRJlbHiMVmxqpJJnjF5Qp55PzDGeZ5nT8mJkJxnvJYr8mN7j_TWI7UdPUc3QWNN--snBU_B0HU7zEYHGiz9YmfT0s1o_eyQrruAjm5tgJF-NBgX8RJndyP4sH9DL77D1Jve3NGracK2h4D0k_Uhudmhg9A_4DHv3EFv4A6fkycdjB5fHOcpuX1_sd18SK5vLq826-tEZ5yHBAQvNTDRFrLuoKpqUWFdArImk4K1wCpZNrrWDeSF6GTDCq1brvOuaWQjZS5PyetD7s7ZbzP6oKbeaxxHMGhnr7jkZZVnRZZFqThItbPeO-zUzvUTuL3iTC381aAW_mrhr1ipIv9oenXMn5v4-F_LH-BR8PYgwPjlQ49Oed2j0RGSQx1Ua_v_57_7x67HCFrD-BX36Ac7OxP5Ka589KjPSwOWAnDBWF4UtfwNNxetPQ</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>El-Gazzar, Yaser, MD</creator><creator>Smith, Daniel C., MD</creator><creator>Kim, Sun Jin, MD</creator><creator>Hirsh, David M., MD</creator><creator>Blum, Yossef, MD</creator><creator>Cobelli, Marcie, FNP</creator><creator>Cohen, Hillel W., DrPH, MPH</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130401</creationdate><title>The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage</title><author>El-Gazzar, Yaser, MD ; Smith, Daniel C., MD ; Kim, Sun Jin, MD ; Hirsh, David M., MD ; Blum, Yossef, MD ; Cobelli, Marcie, FNP ; Cohen, Hillel W., DrPH, MPH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-a217ca02d639fa88928e97ae0b4320da0837bc9cba562f3b06ccd1c5fbb3b3353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Arthroplasty, Replacement, Knee - methods</topic><topic>Cyanoacrylates</topic><topic>dermabond</topic><topic>Drainage</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Orthopedics</topic><topic>Postoperative Period</topic><topic>Prospective Studies</topic><topic>Single-Blind Method</topic><topic>Time Factors</topic><topic>Tissue Adhesives</topic><topic>total knee arthroplasty</topic><topic>Wound Closure Techniques</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El-Gazzar, Yaser, MD</creatorcontrib><creatorcontrib>Smith, Daniel C., MD</creatorcontrib><creatorcontrib>Kim, Sun Jin, MD</creatorcontrib><creatorcontrib>Hirsh, David M., MD</creatorcontrib><creatorcontrib>Blum, Yossef, MD</creatorcontrib><creatorcontrib>Cobelli, Marcie, FNP</creatorcontrib><creatorcontrib>Cohen, Hillel W., DrPH, MPH</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of arthroplasty</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Gazzar, Yaser, MD</au><au>Smith, Daniel C., MD</au><au>Kim, Sun Jin, MD</au><au>Hirsh, David M., MD</au><au>Blum, Yossef, MD</au><au>Cobelli, Marcie, FNP</au><au>Cohen, Hillel W., DrPH, MPH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage</atitle><jtitle>The Journal of arthroplasty</jtitle><addtitle>J Arthroplasty</addtitle><date>2013-04-01</date><risdate>2013</risdate><volume>28</volume><issue>4</issue><spage>553</spage><epage>556</epage><pages>553-556</pages><issn>0883-5403</issn><eissn>1532-8406</eissn><abstract>Abstract Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann–Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level ( P < 0.001).</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>23114193</pmid><doi>10.1016/j.arth.2012.07.038</doi><tpages>4</tpages></addata></record> |
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| ispartof | The Journal of arthroplasty, 2013-04, Vol.28 (4), p.553-556 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Arthroplasty, Replacement, Knee - methods Cyanoacrylates dermabond Drainage Female Humans Male Middle Aged Orthopedics Postoperative Period Prospective Studies Single-Blind Method Time Factors Tissue Adhesives total knee arthroplasty Wound Closure Techniques Wound Healing |
| title | The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage |
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