Very small photoluminescent gold nanoparticles for multimodality biomedical imaging

An original synthesis method based on X-ray irradiation produced gold nanoparticles (AuNPs) with two important properties for biomedical research: intense visible photoluminescence and very high accumulation in cancer cells. The nanoparticles, coated with MUA (11-mercaptoundecanoid acid), are very s...

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Veröffentlicht in:	Biotechnology advances 2013-05, Vol.31 (3), p.362-368
Hauptverfasser:	Lai, Sheng-Feng, Chien, Chia-Chi, Chen, Wen-Chang, Chen, Hsiang-Hsin, Chen, Yi-Yun, Wang, Cheng-Liang, Hwu, Y., Yang, C.S., Chen, C.Y., Liang, K.S., Petibois, Cyril, Tan, Hui-Ru, Tok, Eng-Soon, Margaritondo, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Au nanoparticles Biological and medical sciences biomedical research Biotechnology cell proliferation Cell Proliferation - drug effects Cellular uptake Cytotoxicity Fatty Acids fluorescence Fundamental and applied biological sciences. Psychology Gold Humans image analysis irradiation Light Mass Spectrometry Metal Nanoparticles - ultrastructure Mice Mice, Inbred BALB C microscopy Microscopy - methods Microscopy, Electron, Transmission nanogold nanoparticles neoplasm cells Neoplasms, Experimental - diagnosis Neoplasms, Experimental - pathology Photoluminescence Radiation synthesis Spectroscopy, Fourier Transform Infrared Sulfhydryl Compounds Thermogravimetry Tissue Distribution Tumor Cells, Cultured Tumor development X-radiation X-ray imaging X-Rays
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