Role of CXCR1 (CKR-1) in Inflammation of Experimental Mesangioproliferative Glomerulonephritis

CXCR1 (CKR-1), a receptor of IL-8, is expressed in various cells including neutrophils and monocytes, both of which play a major role in proliferating glomerular diseases. We investigated time-dependent expression of CXCR1 and the effect of single-dose cyclosporine A (CsA) treatment on this expressi...

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Veröffentlicht in:	Renal failure 2013-01, Vol.35 (3), p.380-385
Hauptverfasser:	Ozaltin, Fatih, Besbas, Nesrin, Iskit, Alper Bektas, Cil, Onur, Akcoren, Zuhal, Kale, Gulsev, Bakkaloglu, Aysin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-thymocyte serum chemokine CKR-1 CXCR1 Cyclosporine - pharmacology Cyclosporine - therapeutic use cyclosporine A cytokine Drug Evaluation, Preclinical experimental mesangioproliferative glomerulonephritis Glomerulonephritis, Membranoproliferative - drug therapy Glomerulonephritis, Membranoproliferative - metabolism Kidney - drug effects Kidney - metabolism Male Proliferating Cell Nuclear Antigen - metabolism Rats Rats, Wistar Receptors, Interleukin-8A - metabolism
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