Mismatch repair deficiency in colorectal cancer patients in a low-incidence area

In a previous study we identified 206 patients with colorectal adenocarcinoma in the Northern Cape province of South Africa, diagnosed between January 2002 and February 2009. The age-standardised incidence was 4.2/100 000 per year world standard population. This is 10% of the rate reported in First-...

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Veröffentlicht in:	South African journal of surgery 2013-02, Vol.51 (1), p.16-21
Hauptverfasser:	Vergouwe, F, Boutall, A, Stupart, D, Algar, U, Govender, D, van der Linde, G D, Mall, A, Ramesar, R, Goldberg, P A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adenocarcinoma - epidemiology Adenocarcinoma - genetics Adenocarcinoma - pathology Colorectal cancer Colorectal Neoplasms, Hereditary Nonpolyposis - epidemiology Colorectal Neoplasms, Hereditary Nonpolyposis - genetics Colorectal Neoplasms, Hereditary Nonpolyposis - pathology Diagnosis DNA repair DNA Repair Enzymes - genetics Female Gene Expression Genetic aspects Health aspects Humans Immunohistochemistry Incidence Male Middle Aged MutL Protein Homolog 1 MutL Proteins Neoplasm Proteins - genetics Nuclear Proteins - genetics Risk factors South Africa - epidemiology Yeast
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