Scopolamine as an Antidepressant: A Systematic Review

The cholinergic-adrenergic hypothesis of mania and depression states that depression is characterized by an increase in central cholinergic activity relative to noradrenergic tone. Scopolamine is a centrally acting competitive inhibitor of the muscarinic cholinergic receptor site. This review seeks...

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Veröffentlicht in:	Clinical neuropharmacology 2013, Vol.36 (1), p.24-26
Hauptverfasser:	JAFFE, Robert J, NOVAKOVIC, Vladan, PESELOW, Eric D
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors Acetylcholine receptors (muscarinic) Adult and adolescent clinical studies Affective disorders Antidepressants Antidepressive Agents - therapeutic use Biological and medical sciences Clinical trials Data processing Depression Depressive Disorder - drug therapy Depressive Disorder - epidemiology Depressive Disorder - psychology Geriatrics Humans Intravenous administration Medical sciences Mood disorders Muscarinic Antagonists - therapeutic use Neuropharmacology Norepinephrine Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Randomized Controlled Trials as Topic - methods Replication Reviews Scopolamine Scopolamine Hydrobromide - therapeutic use Statistical analysis
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