Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes

Mitochondria and chloroplasts are major sources of free radical generation in living organisms. Because of this, these organelles require strong protection from free radicals and associated oxidative stress. Melatonin is a potent free radical scavenger and antioxidant. It meets the criteria as a mit...

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Veröffentlicht in:Journal of pineal research 2013-03, Vol.54 (2), p.127-138
Hauptverfasser: Tan, Dun-Xian, Manchester, Lucien C., Liu, Xiaoyan, Rosales-Corral, Sergio A., Acuna-Castroviejo, Dario, Reiter, Russel J.
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Sprache:eng
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