Pseudomonas fluorescens can induce and divert the human β-defensin-2 secretion in intestinal epithelial cells to enhance its virulence

The effect of intestinal molecules produced by the host on the virulence of Pseudomonas fluorescens is poorly documented. In the present work, we evaluated the secretion of human β-defensin-2 (hBD-2) by enterocytes after infection with P. fluorescens (a species previously suggested to be involved in...

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Veröffentlicht in:	Archives of microbiology 2013-03, Vol.195 (3), p.189-195
Hauptverfasser:	Madi, Amar, Alnabhani, Ziad, Leneveu, Charlène, Mijouin, Lily, Feuilloley, Marc, Connil, Nathalie
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - metabolism Anti-Infective Agents - pharmacology beta-Defensins - metabolism beta-Defensins - pharmacology Biochemistry Biomedical and Life Sciences Biotechnology Caco-2 Cells Cell Biology Ecology Enterocytes - metabolism Enterocytes - microbiology Epithelial Cells - metabolism Epithelial Cells - microbiology Humans Inflammatory Bowel Diseases - metabolism Intestines - metabolism Intestines - microbiology Life Sciences MAP Kinase Signaling System - physiology Microbial Ecology Microbiology NF-kappa B - metabolism Original Paper Pseudomonas fluorescens Pseudomonas fluorescens - drug effects Pseudomonas fluorescens - metabolism Pseudomonas fluorescens - pathogenicity Virulence - physiology
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