Label-free methylation specific sensor based on silicon microring resonators for detection and quantification of DNA methylation biomarkers in bladder cancer

Detection and quantification of DNA methylation is important to provide an opportunity to resolve clinical issues such as cancer early detection, progression, and drug treatments. In spite of myriad current technologies for DNA methylation detection that have been developed in last decade, they are...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2013-02, Vol.177, p.404-411
Hauptverfasser:	Shin, Yong, Perera, Agampodi Promoda, Kee, Jack Sheng, Song, Junfeng, Fang, Qing, Lo, Guo-Qiang, Park, Mi Kyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarkers Bladder cancer Cancer biomarker DNA DNA methylation drugs genes humans hybridization Label-free detection Methylation specific sensor promoter regions silicon Silicon microring resonator urinary bladder neoplasms
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