Hypercalcemia Associated with Eosinophilic Myocarditis in a Patient Undergoing Maintenance Hemodialysis
A 77-year-old man previously treated with maintenance hemodialysis was admitted due to appetite loss, nausea and shortness of breath. He showed progressive heart failure and eosinophilia without any basal disorders and was diagnosed with idiopathic hypereosinophilic syndrome (HES) accompanied by eos...
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| Veröffentlicht in: | Internal Medicine 2012, Vol.51(20), pp.2913-2916 |
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| container_title | Internal Medicine |
| container_volume | 51 |
| creator | Tanaka, Ken-ichiro Yano, Shozo Okuyama, Keisuke Sato, Masatake Yamauchi, Mika Yamaguchi, Toru Tanabe, Kazuaki Himeno, Yasutoshi Sugimoto, Toshitsugu |
| description | A 77-year-old man previously treated with maintenance hemodialysis was admitted due to appetite loss, nausea and shortness of breath. He showed progressive heart failure and eosinophilia without any basal disorders and was diagnosed with idiopathic hypereosinophilic syndrome (HES) accompanied by eosinophilic myocarditis. Laboratory data revealed hypercalcemia, a low serum parathyroid hormone level and a high 1,25(OH)2D concentration in spite of renal failure and no causal medications. Steroid therapy resulted in the patient's rapid recovery from heart failure, hypereosinophilia and hypercalcemia. Since the serum 1,25(OH)2D level promptly and markedly decreased, the hypercalcemia complicated with HES was most likely caused by extrarenal production of 1,25(OH)2D. |
| doi_str_mv | 10.2169/internalmedicine.51.8227 |
| format | Article |
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He showed progressive heart failure and eosinophilia without any basal disorders and was diagnosed with idiopathic hypereosinophilic syndrome (HES) accompanied by eosinophilic myocarditis. Laboratory data revealed hypercalcemia, a low serum parathyroid hormone level and a high 1,25(OH)2D concentration in spite of renal failure and no causal medications. Steroid therapy resulted in the patient's rapid recovery from heart failure, hypereosinophilia and hypercalcemia. Since the serum 1,25(OH)2D level promptly and markedly decreased, the hypercalcemia complicated with HES was most likely caused by extrarenal production of 1,25(OH)2D.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.51.8227</identifier><identifier>PMID: 23064567</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Aged ; eosinophilic myocarditis ; hemodialysis ; Humans ; hypercalcemia ; Hypercalcemia - blood ; Hypercalcemia - complications ; Hypercalcemia - diagnosis ; hypereosinophilic syndrome (HES) ; Hypereosinophilic Syndrome - blood ; Hypereosinophilic Syndrome - complications ; Hypereosinophilic Syndrome - diagnosis ; Male ; Myocarditis - blood ; Myocarditis - complications ; Myocarditis - diagnosis ; Renal Dialysis - methods ; steroid ; vitamin D ; Vitamin D - blood</subject><ispartof>Internal Medicine, 2012, Vol.51(20), pp.2913-2916</ispartof><rights>2012 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c560t-dd4dd18a32fd5509f51a6274d0b29a57b9e19d02f4da6091fc2aa1c5841c37793</citedby><cites>FETCH-LOGICAL-c560t-dd4dd18a32fd5509f51a6274d0b29a57b9e19d02f4da6091fc2aa1c5841c37793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23064567$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tanaka, Ken-ichiro</creatorcontrib><creatorcontrib>Yano, Shozo</creatorcontrib><creatorcontrib>Okuyama, Keisuke</creatorcontrib><creatorcontrib>Sato, Masatake</creatorcontrib><creatorcontrib>Yamauchi, Mika</creatorcontrib><creatorcontrib>Yamaguchi, Toru</creatorcontrib><creatorcontrib>Tanabe, Kazuaki</creatorcontrib><creatorcontrib>Himeno, Yasutoshi</creatorcontrib><creatorcontrib>Sugimoto, Toshitsugu</creatorcontrib><title>Hypercalcemia Associated with Eosinophilic Myocarditis in a Patient Undergoing Maintenance Hemodialysis</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>A 77-year-old man previously treated with maintenance hemodialysis was admitted due to appetite loss, nausea and shortness of breath. He showed progressive heart failure and eosinophilia without any basal disorders and was diagnosed with idiopathic hypereosinophilic syndrome (HES) accompanied by eosinophilic myocarditis. Laboratory data revealed hypercalcemia, a low serum parathyroid hormone level and a high 1,25(OH)2D concentration in spite of renal failure and no causal medications. Steroid therapy resulted in the patient's rapid recovery from heart failure, hypereosinophilia and hypercalcemia. Since the serum 1,25(OH)2D level promptly and markedly decreased, the hypercalcemia complicated with HES was most likely caused by extrarenal production of 1,25(OH)2D.</description><subject>Aged</subject><subject>eosinophilic myocarditis</subject><subject>hemodialysis</subject><subject>Humans</subject><subject>hypercalcemia</subject><subject>Hypercalcemia - blood</subject><subject>Hypercalcemia - complications</subject><subject>Hypercalcemia - diagnosis</subject><subject>hypereosinophilic syndrome (HES)</subject><subject>Hypereosinophilic Syndrome - blood</subject><subject>Hypereosinophilic Syndrome - complications</subject><subject>Hypereosinophilic Syndrome - diagnosis</subject><subject>Male</subject><subject>Myocarditis - blood</subject><subject>Myocarditis - complications</subject><subject>Myocarditis - diagnosis</subject><subject>Renal Dialysis - methods</subject><subject>steroid</subject><subject>vitamin D</subject><subject>Vitamin D - blood</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUtrGzEUhUVpaJzHXyhadjOuHqN5bAohpHUhIVk06-FaumPfMCO5kkzxv--4dr0IgXZztdB3zrnSYYxLMVeyaj-Tzxg9DCM6suRxbuS8Uap-x2ZSl21RK23es5loZVOoaZyzi5RehNBN3aoP7FxpUZWmqmdstdhtMFoYLI4E_CalYAkyOv6L8prfhUQ-bNY0kOUPu2AhOsqUOHkO_Akyoc_82TuMq0B-xR9gv5sHb5EvcAyOYNglSlfsrIch4fXxvGTPX-9-3C6K-8dv329v7gtrKpEL50rnZANa9c4Y0fZGQqXq0omlasHUyxZl64TqSwfV9LzeKgBpTVNKq-u61Zfs08F3E8PPLabcjZQsDgN4DNvUSS2noKbS1b9RKZUulfiDNgfUxpBSxL7bRBoh7jopun0j3etGOiO7fSOT9OMxZbucLk_CvxVMwJdX3pby9LHB5wg0_E_C48HgJWVY4SkBYiY74JtCJfbz6HAi7Rpih17_BnAcwVU</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Tanaka, Ken-ichiro</creator><creator>Yano, Shozo</creator><creator>Okuyama, Keisuke</creator><creator>Sato, Masatake</creator><creator>Yamauchi, Mika</creator><creator>Yamaguchi, Toru</creator><creator>Tanabe, Kazuaki</creator><creator>Himeno, Yasutoshi</creator><creator>Sugimoto, Toshitsugu</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QP</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20120101</creationdate><title>Hypercalcemia Associated with Eosinophilic Myocarditis in a Patient Undergoing Maintenance Hemodialysis</title><author>Tanaka, Ken-ichiro ; Yano, Shozo ; Okuyama, Keisuke ; Sato, Masatake ; Yamauchi, Mika ; Yamaguchi, Toru ; Tanabe, Kazuaki ; Himeno, Yasutoshi ; Sugimoto, Toshitsugu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c560t-dd4dd18a32fd5509f51a6274d0b29a57b9e19d02f4da6091fc2aa1c5841c37793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>eosinophilic myocarditis</topic><topic>hemodialysis</topic><topic>Humans</topic><topic>hypercalcemia</topic><topic>Hypercalcemia - blood</topic><topic>Hypercalcemia - complications</topic><topic>Hypercalcemia - diagnosis</topic><topic>hypereosinophilic syndrome (HES)</topic><topic>Hypereosinophilic Syndrome - blood</topic><topic>Hypereosinophilic Syndrome - complications</topic><topic>Hypereosinophilic Syndrome - diagnosis</topic><topic>Male</topic><topic>Myocarditis - blood</topic><topic>Myocarditis - complications</topic><topic>Myocarditis - diagnosis</topic><topic>Renal Dialysis - methods</topic><topic>steroid</topic><topic>vitamin D</topic><topic>Vitamin D - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tanaka, Ken-ichiro</creatorcontrib><creatorcontrib>Yano, Shozo</creatorcontrib><creatorcontrib>Okuyama, Keisuke</creatorcontrib><creatorcontrib>Sato, Masatake</creatorcontrib><creatorcontrib>Yamauchi, Mika</creatorcontrib><creatorcontrib>Yamaguchi, Toru</creatorcontrib><creatorcontrib>Tanabe, Kazuaki</creatorcontrib><creatorcontrib>Himeno, Yasutoshi</creatorcontrib><creatorcontrib>Sugimoto, Toshitsugu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tanaka, Ken-ichiro</au><au>Yano, Shozo</au><au>Okuyama, Keisuke</au><au>Sato, Masatake</au><au>Yamauchi, Mika</au><au>Yamaguchi, Toru</au><au>Tanabe, Kazuaki</au><au>Himeno, Yasutoshi</au><au>Sugimoto, Toshitsugu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypercalcemia Associated with Eosinophilic Myocarditis in a Patient Undergoing Maintenance Hemodialysis</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>51</volume><issue>20</issue><spage>2913</spage><epage>2916</epage><pages>2913-2916</pages><artnum>2913</artnum><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 77-year-old man previously treated with maintenance hemodialysis was admitted due to appetite loss, nausea and shortness of breath. He showed progressive heart failure and eosinophilia without any basal disorders and was diagnosed with idiopathic hypereosinophilic syndrome (HES) accompanied by eosinophilic myocarditis. Laboratory data revealed hypercalcemia, a low serum parathyroid hormone level and a high 1,25(OH)2D concentration in spite of renal failure and no causal medications. Steroid therapy resulted in the patient's rapid recovery from heart failure, hypereosinophilia and hypercalcemia. Since the serum 1,25(OH)2D level promptly and markedly decreased, the hypercalcemia complicated with HES was most likely caused by extrarenal production of 1,25(OH)2D.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>23064567</pmid><doi>10.2169/internalmedicine.51.8227</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aged eosinophilic myocarditis hemodialysis Humans hypercalcemia Hypercalcemia - blood Hypercalcemia - complications Hypercalcemia - diagnosis hypereosinophilic syndrome (HES) Hypereosinophilic Syndrome - blood Hypereosinophilic Syndrome - complications Hypereosinophilic Syndrome - diagnosis Male Myocarditis - blood Myocarditis - complications Myocarditis - diagnosis Renal Dialysis - methods steroid vitamin D Vitamin D - blood |
| title | Hypercalcemia Associated with Eosinophilic Myocarditis in a Patient Undergoing Maintenance Hemodialysis |
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