Co-culture with endothelial progenitor cells promotes survival, migration, and differentiation of osteoclast precursors

► Co-culture of RAW 264.7 monocyte cells with endothelial progenitor cells (EPCs). ► EPCs enhanced survival, migration, and differentiation of RAW 264.7 cells. ► VEGF, SDF-1, and TGF-β1 from EPCs are involved in the regulation of RAW 264.7 cells. ► Presence of EPCs increased expression of VEGFR-2, C...

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Veröffentlicht in:	Biochemical and biophysical research communications 2013-01, Vol.430 (2), p.729-734
Hauptverfasser:	Pang, Hao, Wu, Xue-Hui, Fu, Sheng-Long, Luo, Fei, Zhang, Ze-Hua, Hou, Tian-Yong, Li, Zhi-Qiang, Chang, Zheng-Qi, Yu, Bo, Xu, Jian-Zhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Apoptosis - genetics Apoptosis - physiology Bone turnover Cell Differentiation - genetics Cell Differentiation - physiology Cell Line Cell Movement - genetics Cell Movement - physiology Cell Separation Cell survival Cell Survival - genetics Cell Survival - physiology Co-culture CXCR4 protein Differentiation Endothelial Cells - cytology Endothelial progenitor cells Gene Expression Regulation Leukocyte migration MAP kinase Mice Mice, Inbred C57BL Migration Monocytes Osteoclastogenesis Osteoclasts Osteoclasts - cytology Osteoprogenitor cells RAW 264.7 cells Stem cells Stem Cells - cytology Survival
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